Available Technologies by Category
Innovative Ion Mobility Spectrometry with Open-Air Assembly
  • Protective: Potentially helps protect the technician against contact with ionic hazards
  • Rapid: Separates ions through fast detection of differences in their mass, charge, and cross-section
  • Convenient: Leverages an open-air arrangement that significantly reduces time for experiment setup and sample preparation
4885
High-Tech Infant Suit for Earlier Detection of Cerebral Palsy
  • Advanced: May allow for earlier detection of motor dysfunctions in order to begin therapeutic interventions as soon as possible
  • Robust: Collects data from three limb segments on the leg for a multifaceted assessment
  • Long-lasting: Uses one power source with regulated voltage in order to prolong the use of the device
7949
LoCHAid: An Ultra-Low-Cost and Self-Fitting Hearing Aid
  • Low cost: Uses widely available components that cost 98 cents when purchased in bulk quantities
  • User friendly: Easier to fit—and keep track of—than conventional behind- and in-the-ear hearing aids  
  • Accessible: Designed for easy manufacture and repair in locations where conventional hearing aids are priced beyond the reach of most citizens
7876
Facilitating Ultrasound Penetration of the Skull for Diagnosis and Treatment
  • Portable: Designed to enable imaging of the brain via small, mobile ultrasound devices, which may offer greater convenience compared with MRI and CT machines
  • Affordable: May be a lower cost modality compared with leading techniques, such as MRI, CT, or positron emission tomography (PET)
  • Robust: Demonstrates energy transmission through the skull on par with that of an aqueous medium in preliminary testing
8340
Near-Real-Time Positioning for Instruments and Tools in Magnetic Resonance Elastography (MRE) and Imaging (MRI)
  • Precise: Extremely precise positioning mechanism enables orientation and control capable of sub-millimeter motions within the MR environment
  • Rapid: Significantly speeds up procedure time over standard MRI and offers wavefield images in near real time
  • High resolution: Uses high-frequency actuation to enable imaging of small, geometrically difficult targets
8412
A Partial-Hand Prosthesis Simulator
  • Specific: Designed to maintain limb length by placing artificial fingers in positions similar to where they would be in an intact hand performing grasping actions (rather than extending the length of the limb as many prostheses do)
  • User friendly: Features rubber-capped fingertips that may provide a more lifelike representation of grasp and enhance usability
  • Nuanced: Designed to limit tactile sensation and feedback from immobilized fingers, which may allow better evaluation of how the device is functioning for the patient in comparison to an actual prosthesis
8534
Portable Multi-Parameter Cancer Diagnostic Tool
  • Powerful: Simultaneously measures multiple tissue parameters to determine electro-thermo-mechanical properties
  • Disposable: Uses single-use biochip components to eliminate cross-contamination
  • Versatile: Uses a variety of other micromotion-capable actuators and extends to other manufacturing techniques and different length scales
7619
Next-Generation Custom-Fit Reusable Mask for Respiratory Protection
  • Aims to eliminate fit-testing: Designed to remove the expensive and time-consuming federal (i.e., OSHA) mandate for annual fit-testing for workplace use
  • Improved fit: Adapts to fit specific facial features, increasing comfort and enhancing efficacy and potentially eliminating face-seal leakage to enhance performance
  • Reusable: Withstands cleaning and decontamination
6635
Vest-Style Device Assists Ventilation and Perfusion (V/Q) to Help Prevent Respiratory Failure
  • Powerful: Designed to optimize oxygenation for patients in acute hypoxic respiratory failure
  • Supportive therapy: Non-invasively complements mechanical ventilator support
  • Low cost: Significantly less expensive than technologies that increase oxygenation (e.g., ventilators, oxygen systems)
8529
Novel Crosslinked Hydrogel Improves Efficacy and Side Effects of Cancer Treatment
  • Versatile: Can integrate with all types of immune checkpoint blockade antibodies and respond to various types of cancers
  • Improved tolerability via local delivery: Limits side effects on nonmalignant tissues and organs—a challenge of other immunotherapies
  • Innovative: Leverages the body’s natural immune response to reduce the likelihood of cancer recurrence
8505
Novel Pharmaceutical Compounds Based on Tumor-Selective KDM Inhibitors
  • Selective: Can be used to target specific types of tumors
  • Proven efficacy in vitro: Can be used to inhibit proliferation of cells (e.g., cancer or tumor cells), reducing tumor burden, inhibiting tumor growth, or both
  • Enhanced potency: Displayed a 65-fold increase in cytotoxic potency against tested triple negative breast cancer cell lines
7880
Novel Polymer Hybrid Improves Stability of Implantable Devices
  • Strong: Provides structural stability and enhanced cellular adhesion for implant materials
  • Biocompatible: Reduces the risk for complications that could arise with the use of chemical components
  • Customizable: Permits easy incorporation of various nanomaterials to fine-tune devices to meet patient needs
8449
Powered Bilateral Knee Exoskeleton for Rehabilitation of Children and Adults
  • Lightweight: Uses one of the lightest available electromechanical actuators—just 0.5 kg—along with a mere 1.5 kg for the exoskeleton assembly
  • Back-drivable: Lowers the mechanical effort involved in back driving with a single-stage actuator
  • Efficient: Reduces battery consumption compared with existing systems
8369
Multi-Functional Sparse Phased Arrays for Guiding Focused Ultrasound Therapies
  • Robust: Provides sensitivity of detection down to a single microbubble for FUS-induced microbubble activity
  • Precise: Offers broadband B-mode imaging capabilities to improve workflow and efficacy of FUS-based therapies
  • Scalable: Enables the formation of large CMUT arrays and subarrays with appropriate element spacing
8493
Inverted Organoids for Breast Cancer and Other Invasion Studies
  • Innovative: Serves as a convenient platform for studying the invasive abilities of breast cancer cells
  • Stable: Enables formation of large inverted organoids where the basement membrane forms on the interior surface alongside a breast cell line epithelium
  • Flexible: Allows for long-term studies of at least 25 days due to the robust maintenance of the inverted orientation
8460
Polymer-Based Removal of Pollutants from Contact Lenses
  • Effective: Removes large-particle pollutants as effectively as traditional cleaning solutions, and removes smaller pollutants and microplastics with significantly higher efficacy
  • Robust: Utilizes an elastic polymer that enables contact force between two elastic materials to do the work of removing particles of any size
  • Safe: Eliminates the need for soaking and rubbing removal methods that may tear or damage contact lenses
8398
Assessment of Soluble Cancer Biomarkers for Focused Ultrasound Therapy
  • Simple: Avoids reliance on magnetic resonance imaging (MRI)-based methods of monitoring and optimizing FUS therapy
  • Safe: Relies on a small amount of fluid collected before/after FUS-targeted drug delivery
  • Robust: Enables a range of new therapeutic interventions for cancerous tumors as well as both delivery and monitoring/optimizing of those therapies
8473
Streamlined Hematology Analysis for Point-of-Care Settings
  • Streamlined: Enables testing in point-of-care settings without complex procedures and specially trained personnel
  • Highly accurate: Offers a spatial resolution higher than current methods due to the shorter wavelength of UV light
  • Cost-effective: Saves on reagents, complex equipment costs, and time-intensive processes without compromising diagnostic quality
8303
Technique Improves Printing Quality for 3D Nanoprinting
  • High-performance: Enables a powerful process for high-throughput 3D printing of micro- and nanoscale structures
  • Efficient: Reduces defects during printing to improve yield and decrease excess printing commonly observed with FP-TPL
  • Improved: Broadens the applicability of FP-TPL to printing of functional micro- and nanoscale structures
8478
Super-Absorbent Polymer (SAP) Beads for Collection of Biofluid Samples
  • Fast: Accommodates preloading of specimen collection tubes and completes absorption of analytical targets within a few minutes of fluid collection
  • Low cost: Employs economical materials and eliminates the need for refrigeration of samples while also lowering the weight of samples for transport
  • Easy to use: Avoids the need for filtration, centrifugation, or pipetting and the associated equipment for such tasks
7907