Life Sciences | Office of Technology Licensing

Available Technologies by Category
Devices, Systems, and Methods for Excavating Cancer Cells	Tumors are able to migrate on manufactured fibers or films instead of healthy brain tissue Minimally invasive- the device can be deployed directly or using a catheter The device is size and shape variable- films can range from nano- to micron- scale	5057
Retrieving 3D Information for Probe Microscopy	Can isolate the central region of a diffraction spot from its respective fringes Creates ideal diffraction patterns	3597
Molded Microfluidic Fluid Cell for Atomic Force Microscopy	More precise — Three orders of magnitude decrease in volume of fluid containment when working with the microscope Cost-saving — Allows for the use of less analyte (important for drug companies)	4847
BrainBraille	Increased information bandwidth and speed for BCI devices Rapid learning of motions and associated meanings Enhanced accuracy	8088
Organ Transplant Decision Aid	Simple – easy-to-use interface for entering patient and donor characteristics Flexible – separate survival models use different variables which enhance the performance of each model Multifaceted – calculates survival probabilities for multiple organs where current technologies only determine survival probability for kidneys	8001
Lab-on-a-Headset Ocular Monitoring Device	Low cost Monitor both eyes simultaneously Can be remotely configured	7814
Surface Electrode Ion Trap for Cellular Analysis	Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields Enables sorting of cells by optical, chemical, and/or physical properties Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time	6970
Pterin-Based Hydroxylation of Aromatic Monomers	Could provide substantial high value intermediates Enzymatic catalysis is more energy efficient, yields less (industrial type) waste than chemically based methods Higher level of precision than most chemical reactions	6943
Nanoparticle Modulation of Thrombus Formation	Selective: Operates only in high shear blood flow as in a stenosis Improved Safety: Reduces the risk of bleeding complications from slow bleeds	7466
High Throughput Spectrometer	Low cost – decrease in the number of components decreases cost Compact – decrease in the number of components decreases size High resolution – improvements in hologram recording maintain high resolutions	3548
Integrated Force Sensing for Probe Microscopy	Optimization of the optical detection sensitivity in air or liquid Mini AFM configuration able to form images in very small volumes Multi-tip nanosensors with simultaneous, multifunctional capabilities	3527
PROGNOS: A Web-based Tool for Designing Engineered Nucleases	Algorithm specifically prepared to search entire genomes to identify off-target cleavage sites and design optimal primers for TALENs and ZFNs Available as a simple, user-friendly web-based tool; no extraordinary bioinformatics or biochemical skill required Capable of analyzing TALEN and ZFN sequences targeting human, rat, mouse, zebrafish, arabidopsis, yeast, D melanogaster,	6047, 6058
Ultrasound Methods for Brain Imaging and Therapy	Cost efficient – fast localization, characterization, and control minimize costs Does not require MRI – high-resolution mapping eliminates need for MRI imaging Fast operation – operation can be performed in minutes	8035
Smart Petri Chip: Electronic-Photonic Cellular Sensing Platform	Large-scale throughput, real-time cellular monitoring, and re- usability with no contamination Easily and inexpensively replaced Modules can be designed for various functions	6864
High-Precision Microphone for Body-Worn Devices	Wearable small form-factor (micro-chip technology) Increased sensitivity (micro-gravity sensitivity) Large bandwidth (DC to 10kHz) and wide dynamic range (120dB)	7891
In-Vitro Human Bone Marrow-on-a-Chip	Comprehensive – Reconstructs the three environments of bone marrow, current technologies reconstruct two Quick – Does not require lengthy implantation period within an animal model Personalized – Allows for patient specific drug screening bone marrow tests	7883
Multi-Wavelength Microscopy	Groundbreaking - First noninvasive method of assessing the total cell content of a blood bag without breaching the bag and potentially damaging the contents or compromising manufacturing Cheaper - Laser scanning multi-photon microscopy is 5 to 10 times more expensive Improved Imaging – Consistent cross-section of the cells and reduced blurriness	7862
Fabrication Approach to Impart Anti-Wetting Properties	Does not employ particles to control wetting Approach can be used to modify any material surface Cost-effective	7826
Pulse Width Modulated Periodic Backflush	Cheaper – Extends the usable lifespan of filters More Efficient – Improves recovery percentage by an average of 8.4-fold Versatile – Can be applied to both biological and non-biological systems	7793
Short Distance Gait Pace Meter	Accessible – Large-one-touch buttons, large results font, audible and visible sensor cues Inexpensive – Device components low-cost, installation standard wall-mount Convenient – As simple as recording weight or height: Press a button, walk, record speed.	7783

Technologies