Available Technologies by Category
Antigen-specific Cell Programming Using non-viral Approaches
  • This innovative technology uses synthetic nanoparticles to deliver gene modulators and engineered MHC molecules directly to antigen-specific T cells in vivo, enhancing T cell functions and bypassing ex vivo processes.
  • The prototype improves T cell specificity and reduces off-target toxicity, significantly lowering costs and manufacturing time for effective T cell therapies.
  • It has applications in cancer therapy, immune therapy, autoimmune disease therapy, and infectious disease therapy.
8703
Engineering Antigen-Specific T Cells for CAR T Cell Therapy via Antigen-Presenting Lipid Nanoparticles
  • Technology Overview: Georgia Tech's new CAR T cell therapy uses lipid nanoparticles (LNPs) to program antigen-specific T cells in vivo, potentially reducing costs and production time.

  • Advantages: This approach avoids expensive and time-consuming ex vivo manufacturing, minimizes off-target effects, can adapt to various CAR constructs and cancer types, and promises rapid scaling and reduced costs.

  • Commercial Applications: Applicable to multiple myeloma, CD19+ cancers, and a wide range of other cancers, this technology streamlines CAR T cell therapy manufacturing for faster, more affordable treatments.

9386
Recyclable Organic Solar Cells On Substrates Comprising Cellulose Nanocrystals (CNC)
  • The novel invention utilizes cellulose nanocrystals to create efficient organic solar cells with substrates that are renewable and exhibit strong mechanical and optical properties, achieving a high power conversion efficiency.
  • The solution offers an environmentally friendly alternative to traditional silicon-based solar panels by being flexible, low-cost, biodegradable, and easily recyclable at room temperature.
  • The innovation is suitable for commercial uses in low-cost electronics, biodegradable printed electronics, wearables, IoT applications, and sustainable building designs.
6304
Scalable Manufacturing Approach of Graded Polymer Thin Film Has Potential for Widespread Use
  • Combines slot die coating with a custom roll-to-roll imaging system to allow for efficient, rapid, and scalable fabrication of high-quality gradient thin films.
  • An improved manufacturing process over existing techniques because it uses broad material combinations and yields higher quality patterned thin films.
  • Incorporates multiple materials to increase the application of patterned thin films across industries, including microelectronics, energy technologies, and environmental systems.
8994
Leverage the Advantages of Aluminum Nitride for Superior Ultra-Wide Bandgap Semiconductors for High-Power, High-Temperature Diodes and Transistors
  • Metal modulated epitaxy method enables the production of p-type beryllium-doped aluminum nitride films as key components in ultra-wide bandgap semiconductors for the first time. 
  • Achieves high reverse breakdown voltage—a significant advantage over wide bandgap materials such as silicon carbide and gallium nitride.
  • Improves current conduction over best previous results in p-type aluminum nitride (AIN) by 30,000,000 times and n-type AlN by 6,000 times.
8666
Tunable Membrane-Based Wastewater Treatment and Resource Recovery
  • Customizable membrane structure and surface properties provide selective removal of contaminants of emerging concerns (CEC) and recovery of valuable components.
  • An enlarged membrane surface area, combined with a gutter effect from the interlayer, results in nearly double the water permeability of current filtration membranes.
  • Achieves high-performance recovery of essential nutrients/fertilizers that are free of CECs.
8633
Lymphatic System-Specific Lipid Nanoparticles
  • This platform technology improves current targeting to lymphatic tissues and specifically lymphatic endothelial cells.
  • Provides superior tissue targeting and functional delivery of mRNA to lymphatics via loco-regional dermal or subcutaneous avenues.
  • mRNA-based platforms offer a transient and less immunogenic method of delivery compared to protein therapeutics or adeno-associated virus-based platforms.
9056
Superluminescent Light Projection (SLP) System Decreases Nanoscale Printing Costs by 10–50 Times
  • This superluminescent light projection (SLP) system decreases overall nanoscale printing costs by 10–50 times. 
  • A parallel writing mechanism supports higher throughput speeds: up to 100 times higher than existing metal printing methods and four times higher than existing polymer printing methods. 
  • SLP creates sharp-edged images with minimal speckling patterns, resulting in high-resolution images and structures on both polymer and metal-based films. 
9066
Sustained Lymphatic Drug Delivery System Potentially Improves Efficacy and Safety of Immunotherapy and Targeted Therapies
  • This sustained lymphatic drug delivery system guides therapeutics and imaging agents to the injection site, lymphatic vessels, and lymph nodes. 
  • Sustained lymphatic delivery enables lower dosing and fewer administrations to potentially improve therapeutic response while reducing adverse effects and costs.
  • The simplicity of a vaccine-like, sustained drug release injection allows use at less expensive community health centers.
8637
Electric Field Treatment Creates Safe, Effective Antimicrobial Surfaces
  • Creates safe, effective antimicrobial surfaces via bacteria inactivation without the use of chemicals
  • Targets cell membranes or capsid, is less likely to induce antimicrobial resistance, and should be effective for antibiotic-resistant bacteria
  • Requires very short electrical pulses to achieve effective bacteria inactivation, potentially leading to better antifouling performance
9130
Microrobots for Neurosurgery Applications
  • Minimally invasive: Significantly reduces invasiveness of procedures in comparison to current macroscale, neurosurgical robots 
  • Precise control: Uses 3D position data of the microrobots on the brain surface in a closed-loop system to adjust the magnetic field parameters (i.e., magnitude, frequency, phase, and direct current [DC] offset of each coil) as well as the forces the robots exert to the biopsy tissue
  • Facilitates movement: Employs microfabricated shapes that dictate the microrobot's movements, limits their contact with the brain surface to reduce adhesion, and may also provide a means for the robot to propel itself in fluid
8749
Cluster-Wells: Isolating Aggressive Tumor Cell Clusters for Improved Cancer Diagnosis and Treatment
  • High performing: Demonstrates superior abilities to isolate CTCs without clogging the system or dissociating the clusters
  • Low cost: Shows high potential for large-scale production because it uses simple equipment and a straightforward process
  • Versatile: Isolates CTC clusters of any cancer type and uses hardware that can be modified to accommodate various devices
8203
Low-Power Real-Time Ionizing Radiation Detector
  • Sensitive: Detects the charge generated from the interactions of ionizing radiation within matter with a high level of precision and discerns X-ray pulses of varying dose
  • Scalable: Covers a significantly larger detection area than other methods, ranging from 60,000 square micrometers to one square millimeter
  • Responsive: Responds within microseconds and proportionately with the overall radiation dose when exposed to X-rays of varying tube voltage (energy) and tube current (number of particles)
8780
Self-Powered Highly Stretchable Sensing Interface for Gesture Recognition
  • Self-contained: Includes a signal processing pipeline, providing gesture recognition for an extensive range of input modalities without the need for external power or sensing equipment
  • Assistive: Enables eyes-free, unobtrusive, and ergonomic interaction with computing devices embedded in wearables
  • Versatile: Demonstrates far-reaching potential for applications beyond gesture recognition including in actuation and data acquisition
7987
Integrated Alkali Dispenser Collimator
  • Precise: Reducing the “spread” of vapor via collimation can reduce potential signal-to-noise ratio degradation and avoid contamination of nearby electronic components.
  • Simple: Generating a directed atomic beam from the dispenser can be achieved via integrated packaging.
  • Cooler: Placing a spacer material between the dispenser and collimator creates a sealed gap that not only prevents leakage, but also allows the vapor to cool (via rapid thermalization with the collimator plate).
8872
Superior Supercapacitors
  • High performance: Achieves average energy densities as high as 90 Wh/Kg
  • Scalable: Leverages a low-cost PAN fabrication process that dramatically increases surface area
  • Widely applicable: Demonstrates potential for advances in a variety of energy storage and capacitive water desalination applications
6201
Skin-Conformal Wearable Stress Monitor Delivers Greater Precision and Continuous, Wireless Monitoring with Comfort and Flexibility
  • All-in-one: The personal adhesive bandage-like single device platform offers wireless, multi-data sensing by simply mounting it on the skin.
  • Disposable: This wearable device is fully disposable after the use and the measured data can be simply sent to the cloud via a tablet or smartphone app.
  • Compact: The unique, thin design of this bioelectric device is one-sixth the volume of current market offerings—weighing less than 7 g, including its rechargeable battery.
8414
Purely Passive Radio-Frequency Identification
  • Powerful: Projected to support energy harvesting sensors at distances over 100 meters from readers and/or radio transmission sources
  • Efficient: Enables conversion of RF energy at higher efficiency and at higher output voltages than current electronic energy harvesting methods
  • Widely applicable: May advance RFID applications in a wide range of fields including computing, sensing, and communication
7194
Sustainable Combination Technology Delivers a Long-Lasting Self-Powered Battery
  • Continuous: Regulates power harvested in the presence of constant mechanical motion to store excess energy while pushing a constant voltage to the external load
  • Eco-friendly: Reduces the need for consumers and technology developers to utilize supply-limited traditional batteries that are thrown away after a short use and could leak harmful chemicals into the environment
  • Sustainable: Eliminates the need to mine an additional power supply by harvesting energy from underutilized electrostatic induction found in naturally occurring mechanical motion
6418
Heat Dissipation for Microelectronic Systems via Capillary Trap
  • Effective: Dissipates large heat fluxes via 3D heat spreading and evaporative cooling that could approach kW/cm2 and beyond while keeping the surface temperature under 90oC
  • Preventive: Mitigates coolant dry-out at the critical heat flux levels that result in a rapid and large temperature rise and thus cause device burn-out
  • Efficient: Exploits high cooling capabilities associated with phase-change heat transfer through evaporation
6272