Life Sciences | Office of Technology Licensing

Available Technologies by Category
KIDSCRRT – A Device for Continuous Renal Replacement Therapy in Children	Pediatric-friendly- elimination of existing application of adult CRRT devices for pediatric care Improved accuracy- novel pump and control system design complete with offset loop and fluid balance system Versatile- easily integrated with other extracorporeal therapies	5363
Alveolar Breath Separation and Collection Device	Simple: this device has fewer components than prior devices Inexpensive: this device is less expensive than previous devices due to its simpler design	4734
Patterning of Superhydrophobic Paper Surfaces	Versatile – allows for flexibility of paper and any array of “sticky” dots and lines Simpler – space saving alternative to three-dimensional microfluidic products Cheaper – made using paper and simple application process for “sticky” regions	4729
Periodic Arrays for Frequency-Based Beam Steering	Avoids individual control of array components Reduced cost, smaller design equipment	4716
System for Bone Regeneration	Provides superior retention and release of osteoinductive protein Reduces necessary dose of osteoinductive protein Reduced cost of procedure	4660
Improved AZA-peptide Epoxides	Versatile: able to treat multiple diseases Can be administered with or without other protease inhibitors	3738
Method for Packaging Advanced Sensors and Electronics	High volume — device can be used for simultaneous sensing of thousands of proteins or nucleic acid sequences Cheaper — utilizes low cost wafer-scale semiconductor manufacturing technologies Versatile — can be used for many chemical and biochemical sensors	4514
Fluorescent Nanoprobes for Live-Cell RNA Imaging	Sensitive — can image single molecules with multiple emission wavelengths Fast — probe is multivalent and bind to RNA in less than 10 minutes Low cost — the alternative dual-label probes are more expensive	4513
Replaceable Heart Valve Prosthesis	Repeatable- method may be repeated multiple times Versatile- mechanism may substitute more than one valve Lower-cost	3692
Method for Minimally Invasive Heart Valve Procedures	Minimally invasive: heart valve repair system breakdown allows for a smoother process Futuristic: eliminates the need for cardiopulmonary bypass Reduced risk: intends a lower mortality rate during procedure	4483
Core-Shell Nanogel Cellular Delivery Vehicles	Delivery of a broad range of various materials to cells Higher payloads and faster and more sustained RNA interference than non-targeted commercial siRNA delivery vehicle Less toxic than commercial liposomal formulations	4480
Method to Control the Annular Septal-Lateral Diameter of a Valve	Minimally invasive- tools for SLAC deployed endovascularly, percutaneously, or thorocoscopically through a catheter Effective- reduces the septal-lateral diameter on the mitral valve Biocompatible- provides an anchoring system for anchoring a minimally invasively deployed annuloplasty ring	3690
Carbon Nanotube Electrode Array for Neural Prosthetics	Densely packed CNT arrays allow for better bio-incorporation, prevention of glial scarring, chronic inflammation, and neuronal cell loss Readily functionalized to promote neuronal growth and tissue-electrode adhesion, enhancing electrode performance and quality of read-out signals Inherent mechanical stiffness enhances the rigidity of adjacent CNTs preventing buckling as in other high-aspect probe systems.	4434
Reduced Cyanine Dyes	Simple Synthesis - Easy one-step synthesis from commercially available cyanine dyes Dependable - Exceptional sensitivity Versatile - High stability and wide range wavelength tunability	4430
Chemically Resolved Microscopy Using Microplasma Discharges	Can be operated under ambient temperature and pressure Higher chemical and spatial resolution than currently exists Has the ability to pair mass spectrometry to microscopy	4340
Cell-Free Biomaterial for Tissue Regeneration and Repair	Simple — does not require difficult or extensive preparation Regenerative — provides unique molecular cues similar to early embryogenesis, enabling directing of cell differentiation and tissue morphogenesis Compatible and customizable — can be tailored for specific tissue applications by directing the differentiation of the ES cells prior to acellularization	3662
Scatter Correction for Cone-beam CT in Radiation Therapy	Does not modify either the hardware or the imaging protocols of the clinical system Effectively reduces the scatter signals in the CBCTY scan, and improves image quality Does not require an increase in the dose to the patients	5135
A Biodegradable Polymer for Medical Applications	Adaptive and applicable – mechanical properties can be tailored to the desired medical application Controlled biodegradation- biodegradation profile is easily adjustable	5121
Microneedle Coating	Alternative method for hypodermic needles Coating uniformity Spatial control on coating length	3526
Automated Medical Image Interpretation for Tissue Segmentation	Increased accuracy: Computer processing removes the need to manually interpret boundaries Fast: The algorithm is extremely rapid, repeatable, and accurate Versatile: Programs can be implemented in assembly or machine language	5107

Technologies