| Functionalized Nanowires for miRNA-mediated Programming of Naive T Cells |
- Technology Overview: Georgia Tech's functionalized nanowires deliver genetic materials like miRNAs and CRISPR directly to naive T cells, enhancing their therapeutic potential without pre-activation.
- Advantages: This method preserves the naive state of T cells, allowing for better viability and functionality, reduced exhaustion, and delivery of both small and large biomolecules, including lentiviral particles.
- Commercial Applications: The technology can be used in adoptive T cell therapy for cancer and infectious diseases, therapeutic delivery of biomolecules, and as a research tool for immune cell manipulation.
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9341 |
|
| Organic Molecules with Delayed Fluorescence for Human-Centric Lighting and Radiation Detectors |
- Innovative light converter tech mimics natural daylight using organic molecules with delayed fluorescence, surpassing current solutions.
- The technology addresses health issues caused by artificial lighting, offering stable, energy-efficient human-centric lighting.
- It has versatile applications include indoor lighting, therapy for mood disorders, and smart lighting systems.
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2024-080 |
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| Nanocomposite Film for Volatile Organic Compound Sensing |
- The invention is a new type of chemoresistor capable of sensing volatile organic compounds (VOCs).
- The chemoresistor is comprised of a conductive nanoparticle surrounded by a polymer matrix which allows for the chemoresistor’s
resistance, sensitivity, and target VOC to be adjusted. - The nanocomposite can be placed on electrodes through drop casting, dip coating, and painting, which provides a cheap, simple and sensitive sensor ideal for fieldwork.
|
8695 |
|
| Novel Hydrogels for Encapsulation, Vascularization, and Transplantation of Cells |
- This hydrolytically degradable poly(ethylene glycol) (PEG) hydrogel leverages ester linkages combined at various ratios with non-degradable macromers to enable tunable degradation kinetics.
- Potential applications include controlled release and delivery of drugs or proteins as well as cell encapsulation. It can also be used as a delivery vehicle and adhesive for cells in transplantation settings.
- These innovative hydrogels allow for rapid hydrolytic cleavage in vivo but remain stable in vitro for weeks at neural pH 7 to support regenerative medicine techniques.
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9019 |
|
| Composite Hybrid Electrode Material Composed of Alumina, Titania, and Carbon Nanotubes |
- The invention is a new composite electrode material designed for use in supercapacitors.
- The innovation is composed of a hybrid composite material with a thin coating of alumina and titania which allows energy storage systems to have increased energy density, power density, and cycle life.
- The new composite hybrid electrode is fit for use in renewable energy systems, consumer electronics, aerospace and defense, and can provide a more efficient solution.
|
9247 |
|
| Recyclable Organic Solar Cells On Substrates Comprising Cellulose Nanocrystals (CNC) |
- The novel invention utilizes cellulose nanocrystals to create efficient organic solar cells with substrates that are renewable and exhibit strong mechanical and optical properties, achieving a high power conversion efficiency.
- The solution offers an environmentally friendly alternative to traditional silicon-based solar panels by being flexible, low-cost, biodegradable, and easily recyclable at room temperature.
- The innovation is suitable for commercial uses in low-cost electronics, biodegradable printed electronics, wearables, IoT applications, and sustainable building designs.
|
6304 |
|
| Scalable Manufacturing Approach of Graded Polymer Thin Film Has Potential for Widespread Use |
- Combines slot die coating with a custom roll-to-roll imaging system to allow for efficient, rapid, and scalable fabrication of high-quality gradient thin films.
- An improved manufacturing process over existing techniques because it uses broad material combinations and yields higher quality patterned thin films.
- Incorporates multiple materials to increase the application of patterned thin films across industries, including microelectronics, energy technologies, and environmental systems.
|
8994 |
|
| Leverage the Advantages of Aluminum Nitride for Superior Ultra-Wide Bandgap Semiconductors for High-Power, High-Temperature Diodes and Transistors |
- Metal modulated epitaxy method enables the production of p-type beryllium-doped aluminum nitride films as key components in ultra-wide bandgap semiconductors for the first time.
- Achieves high reverse breakdown voltage—a significant advantage over wide bandgap materials such as silicon carbide and gallium nitride.
- Improves current conduction over best previous results in p-type aluminum nitride (AIN) by 30,000,000 times and n-type AlN by 6,000 times.
|
8666 |
|
| Tunable Membrane-Based Wastewater Treatment and Resource Recovery |
- Customizable membrane structure and surface properties provide selective removal of contaminants of emerging concerns (CEC) and recovery of valuable components.
- An enlarged membrane surface area, combined with a gutter effect from the interlayer, results in nearly double the water permeability of current filtration membranes.
- Achieves high-performance recovery of essential nutrients/fertilizers that are free of CECs.
|
8633 |
|
| Overvoltage Surge Protection System for Distributed Energy Resources |
- iMOV is a dynamic system capable of achieving voltage surge clamping within 20% of the system’s nominal voltage. This effectively provides protection for highly sensitive semiconductors present in DER-associated power converters.
- This system is built upon a metal oxide varistors (MOV) foundation, whose material composition inherently allows rapid device connection of 500 picoseconds for quicker response times.
- iMOV uses integrated microprocessors and sensors in a cloud-based architecture that provides protection against cyberattacks, reduces system cost, and allows system and power grid monitoring.
|
9190 |
|
| AI-Designed High Energy–Density High-Temperature Polymers |
- The present materials are capable of withstanding enormous electric fields at very high temperatures.
- The materials produced are extremely lightweight.
- Vehicles making use of these materials will be lightweight, and lighter vehicles consume less energy.
|
9101 |
|
| Microgeodes Enable Tunable Optical Response for Advanced Coatings/Paint |
- Microgeodes have a programmable structure of nanowires that allows their optical response to be engineered precisely over multiple spectral bands, from UV through mid-IR.
- Microgeodes combine the tunability and versatility of nanowires with the processability of microspheres to provide a photonic materials platform for a wide range of applications.
- Microgeode paints could reduce building surface temperatures by as much as 25°C, offering the potential for significant consumer savings while retaining aesthetically pleasing colors.
|
8866 |
|
| Lymphoid Tissue System Harnesses Ex Vivo Immune Reactions for Rapid Antibody Production and Immune Response Prediction |
- This immunocompetent system uniquely accounts for the unexpected activation of various immune cells to allow proper immune cell differentiation, recapitulating an effective immune response.
- The chemokine gradient is switchable, allowing the immune cell differentiation needed for an appropriate immune reaction.
- An ex vivo system supports immune response creation in a controlled environment, allowing reproduction of immunologic events for developing improved therapeutics.
|
9196 |
|
| Solar Cell Manufacturing Technique Increases Efficiency and Lowers Costs |
- This double-side polysilicon/silicon oxide TOPCon (tunnel oxide passivated contact) solar cell concept provides a simple and low-cost way to passivate front and back surfaces of silicon wafers to enhance efficiency.
- Provides current and voltage comparable to full-area double-side TOPCon but with no appreciable absorption in front polysilicon and without compromising short circuit current density
- Includes a novel and fast way to pattern polysilicon using laser-induced selective oxidation
|
8888 |
|
| Bioabsorbable, Permeable, and Flexible 3D Auxetic Implants Offer Large-Volume Soft Tissue Reconstruction |
- A novel 3D auxetic architecture offers enhanced compressive flexibility, permeability, and nonlinear mechanical behavior.
- This high-performance technology has the potential to generate implants with soft tissue-mimetic biomechanical properties and high mass transfer capacity.
- Implants can be customized for patients by adjusting the strut width and intervals and by fitting the complex anatomic geometry of the defect based on patient medical data.
|
8821 |
|
| Tunable MEMs Gas Sensor Improves Selectivity and Sensitivity |
- Versatile: Customizes MEMS chemical sensors, compatible with a variety of sensing materials, allowing for the detection of numerous gas-phase analytes
- Easy to manufacture: Uses batch-fabricated sensors compatible with COTS electronics
- Highly sensitive: Offers sub parts-per-million detection limits for volatile organic compounds
- Enhanced selectivity: Combines gravimetric and impedimetric responses to demonstrate enhanced discrimination between multiple VOCs
- Powerful: Enables the simultaneous observation of both mass loading and dielectric changes in polymeric sensing films upon sorption of an analyte
- Innovative: Uses the transient response characteristics of a sensor response to a gated exposure event, rather than steady-state sensor data
|
8269, 8987 |
|
| Catalyst for Degradation of Traditional PET |
- Degradation of PET products lead to less landfill waste.
- The technology has applications in bio-based packaging to eliminate single-use plastics.
- Degradation does not give rise to microplastics, which are hazardous.
|
8960 |
|
| Superluminescent Light Projection (SLP) System Decreases Nanoscale Printing Costs by 10–50 Times |
- This superluminescent light projection (SLP) system decreases overall nanoscale printing costs by 10–50 times.
- A parallel writing mechanism supports higher throughput speeds: up to 100 times higher than existing metal printing methods and four times higher than existing polymer printing methods.
- SLP creates sharp-edged images with minimal speckling patterns, resulting in high-resolution images and structures on both polymer and metal-based films.
|
9066 |
|
| Patient-Centered Biofeedback Headset Can Isolate, Monitor, and Analyze Vocal Output in Real Time for Optimal Voice Modulation in Patients with Parkinson’s Disease |
- Innovative headset offers real-time haptic feedback for vocal improvement and increased patient autonomy.
- Device stores easily accessible data for therapist review and fine-tuning of preset therapeutic thresholds to continually improve vocal output.
- Lightweight, low-profile, battery-powered headset are favorable for all-day wear and use omnidirectional microphones for optimal comfort.
|
9134 |
|
| Hydrogel-Based Artificial Ligaments Offer Substantial Improvements for ACL Reconstruction Therapies |
- This biocompatible hydrogel-based device is designed to reproduce natural ligament/tendon function to decrease the incidence of immune responses that lead to chronic inflammation.
- An alternative to standard artificial ligaments and tendons, the device is designed to be placed via non-invasive techniques, making it a safer alternative to current, invasive surgical methods.
- Non-biodegradable hydrogels are highly durable, potentially increasing the lifespan of the prostheses.
|
5386 |
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