| Nanocomposite Film for Volatile Organic Compound Sensing |
- The invention is a new type of chemoresistor capable of sensing volatile organic compounds (VOCs).
- The chemoresistor is comprised of a conductive nanoparticle surrounded by a polymer matrix which allows for the chemoresistor’s
resistance, sensitivity, and target VOC to be adjusted. - The nanocomposite can be placed on electrodes through drop casting, dip coating, and painting, which provides a cheap, simple and sensitive sensor ideal for fieldwork.
|
8695 |
|
| Scalable Manufacturing Approach of Graded Polymer Thin Film Has Potential for Widespread Use |
- Combines slot die coating with a custom roll-to-roll imaging system to allow for efficient, rapid, and scalable fabrication of high-quality gradient thin films.
- An improved manufacturing process over existing techniques because it uses broad material combinations and yields higher quality patterned thin films.
- Incorporates multiple materials to increase the application of patterned thin films across industries, including microelectronics, energy technologies, and environmental systems.
|
8994 |
|
| Leverage the Advantages of Aluminum Nitride for Superior Ultra-Wide Bandgap Semiconductors for High-Power, High-Temperature Diodes and Transistors |
- Metal modulated epitaxy method enables the production of p-type beryllium-doped aluminum nitride films as key components in ultra-wide bandgap semiconductors for the first time.
- Achieves high reverse breakdown voltage—a significant advantage over wide bandgap materials such as silicon carbide and gallium nitride.
- Improves current conduction over best previous results in p-type aluminum nitride (AIN) by 30,000,000 times and n-type AlN by 6,000 times.
|
8666 |
|
| Smart Nanosensor-Embedded Stent System for Wireless Surveillance of Restenosis in Coronary Artery Disease |
- An electronic stent that incorporates an ultrathin stretchable wireless sensor for continuous surveillance of restenosis along with neointimal proliferation and plaque deposition.
- There is no existing system that offers a clinically practical solution for continuous, real- time detection of both restenosis incidence and progression.
- This device will profoundly decrease the number of healthcare dollars spent on repeated revascularization due to restenosis in CAD.
|
8542 |
|
| Enabling Rapid Detection of Label-Free RNA for Use in COVID-19 Testing |
- Earlier detection: Identifying the viral components themselves—rather than the body’s reaction to the viral presence (i.e., antibodies)—potentially improves early detection in asymptomatic subjects.
- Simpler process: Use of minimal reagents and fewer preparatory steps is designed to enable more efficient and facile sample preparation. Avoidance of “wash steps” aims to minimize target loss.
- Fewer disruptions: Avoiding the use of high-demand supplies (e.g., swabs) and reagents potentially reduces supply-chain and contamination issues.
|
8669 |
|
| Messenger Ribonucleic Acid (mRNA)–Based Opsin Expression Enables New and Safer Optogenetic Studies |
- Opsin expression using messenger RNA (mRNA) provides an alternative to viral vectors for use in optogenetic studies involving neurons as well as drug testing with cardiomyocytes.
- Expression with mRNAs has lower toxicity and is usually detectable within 2–24 hours rather than 2–3 weeks.
- The controllable and temporary nature of mRNA offers improved expression regulation based on the transfection amount.
|
7534 |
|
| Overvoltage Surge Protection System for Distributed Energy Resources |
- iMOV is a dynamic system capable of achieving voltage surge clamping within 20% of the system’s nominal voltage. This effectively provides protection for highly sensitive semiconductors present in DER-associated power converters.
- This system is built upon a metal oxide varistors (MOV) foundation, whose material composition inherently allows rapid device connection of 500 picoseconds for quicker response times.
- iMOV uses integrated microprocessors and sensors in a cloud-based architecture that provides protection against cyberattacks, reduces system cost, and allows system and power grid monitoring.
|
9190 |
|
| Monitor Vehicle Location and Maintain Vehicle Health During Long-Term Storage |
- Vehicle health and location monitoring system automatically establishes a mesh network for vehicle fleet monitoring by a human, drone, or mobile robot.
- Checks battery and other vehicle health status as well as determines locations of all connected vehicles in storage.
- When a vehicle is found with low battery levels, a mobile robot can safely provide a charge to the battery to get the vehicle running.
|
8938 |
|
| Soft Wireless Sternal Patch for Detecting Systemic Vasoconstriction Using Photoplethysmography |
- A wireless, soft sternal patch includes integrated skin-like, photolithographically patterned electronics specifically tuned to continuously measure vasoconstriction from the sternum.
- In overnight trials, the device detected sleep apnea and hypopnea with 95% precision and 100% sensitivity compared to data professionally scored by licensed clinicians.
- Use of this patch on the chest could improve detection of key markers of numerous harmful health conditions.
|
9170 |
|
| Targeted Single Cell Electroporation for Gene and Cell Therapy |
- The technology enables high efficiency delivery and high post-electroporation cell viability compared to current commercial electroporation systems.
- The technology performs in-flow single cell measurements integrated with electroporation unlike current commercial electroporation systems which have no single cell measurement capabilities.
- The technology enables automatic feedback control and real-time optimization of electroporation parameters at the single-cell level unlike current commercial electroporation systems which apply the same parameters to all cells in a batch at a bulk scale.
- The technology enables selected or targeted electroporation and delivery to selected cells or cell types from a mixture of cells unlike current commercial electroporation systems which require upstream or downstream cell sorting steps.
|
9086 |
|
| Tunable MEMs Gas Sensor Improves Selectivity and Sensitivity |
- Versatile: Customizes MEMS chemical sensors, compatible with a variety of sensing materials, allowing for the detection of numerous gas-phase analytes
- Easy to manufacture: Uses batch-fabricated sensors compatible with COTS electronics
- Highly sensitive: Offers sub parts-per-million detection limits for volatile organic compounds
- Enhanced selectivity: Combines gravimetric and impedimetric responses to demonstrate enhanced discrimination between multiple VOCs
- Powerful: Enables the simultaneous observation of both mass loading and dielectric changes in polymeric sensing films upon sorption of an analyte
- Innovative: Uses the transient response characteristics of a sensor response to a gated exposure event, rather than steady-state sensor data
|
8269, 8987 |
|
| Quantum Tunneling Radio Positioning System Achieves Higher Levels of Accuracy and Longer Range for Next-Generation Wireless Networks |
- This radiolocation system uses quantum tunneling tags (QTT) capable of operating in non-line-of-sight conditions to achieve longer range communications in outdoor and indoor applications.
- The use of QTTs, paired with a frequency hopping reader, results in positioning accuracy not achievable with standard methods.
- QTTs are inexpensive and operate under low power requirements to offer an affordable orientation system with long battery life.
|
8535 |
|
| Patient-Centered Biofeedback Headset Can Isolate, Monitor, and Analyze Vocal Output in Real Time for Optimal Voice Modulation in Patients with Parkinson’s Disease |
- Innovative headset offers real-time haptic feedback for vocal improvement and increased patient autonomy.
- Device stores easily accessible data for therapist review and fine-tuning of preset therapeutic thresholds to continually improve vocal output.
- Lightweight, low-profile, battery-powered headset are favorable for all-day wear and use omnidirectional microphones for optimal comfort.
|
9134 |
|
| Universal Transcriptional Programming in a Bacteroides Consortium Creates a Foundation to Advance Living Therapeutics |
- Consortium-based, universal transcriptional programming framework is a biotic decision-making technology using genetic circuit compression in a Bacteroides community.
- Compressed genetic circuit design shortens circuit-building time, offers a compact circuit footprint that allows more complexity, uses fewer resources, and reduces cell communication time.
- Has potential applications in living therapeutics, advanced biomanufacturing, and next-generation biosecurity.
|
9006 |
|
| Foot Ankle Orthotic (FAO) Delivers Real-Time Portable, Discreet Haptic Feedback for Patients and Athletes |
- Providing patients with discreet notifications of real-time plantar pressure to improve rehabilitation of foot-ankle injuries between clinical visits can reduce risk of injury strain and minimize long-term damage.
- Athletes from various sports (e.g., tennis, football, basketball) could prioritize injury prevention during practice and games because of the discreet haptic notifications that bring attention to foot planting techniques via pressure monitoring.
- The benefits of measuring plantar pressure from the four zones of this device’s insole (heel, toes, medial, and lateral) extend beyond foot-ankle injuries and can be key to diabetic pressure wound prevention as well as knee osteoarthritis therapy.
|
8944 |
|
| Portable, Reusable, Micropower Radiation Monitors Provide Real-Time Assessment of Radiation Risk |
- Innovative radiation detection system provides real-time, on-demand, micropower detection in a versatile design.
- The device materials offer higher conductivity (mobility) than silicon, resulting in reduced power needs (i.e., requiring power only during read-out).
- Selection and layering of channel and gate materials enables tuning devices for different radiation types.
|
8084 |
|
| Custom-Fit Reusable Respiratory Protective Device (RPD) with Continuous Fit Monitoring Improves Comfort and Protection |
- Vastly improves comfort and protection while bringing peace of mind to wearers through a custom fit and continuous monitoring
- Reduces pressure injuries caused by extended RPD use through both a customized fit and alerts to the wearer when the RPD should be adjusted or removed
- Minimizes exposures to workplace hazards by immediately detecting leakage during RPD use and alerting the wearer to adjust the device
|
8876, 9089, 9090, 9091 |
|
| “Smart” Feedback-Controlled Bioreactor Platform Enables Consistent High-Yield and High-Quality MSC Products |
- Scaled-down feedback-controlled hollow fiber-based bioreactor enables identifying the critical quality attributes and critical process parameters for high-quantity and high-quality hCT-MSCs for ideal cell growth and efficacy
- Provides the controls to maintain optimum conditions and improve expansion yield and cell viability
- System can be adapted and applied to industrial cell therapy manufacturing and can enable high-yield and high-quality products while minimizing variabilities
|
8887 |
|
| High-Precision, Hands-Free Remote Control of Complex Robotic Systems Via Eye Movements |
- This two-camera eye-tracking system (TCES) integrates a commercial eye tracker with machine-learning technology for continuous real-time classification of gaze and eye directions for robotic arm control.
- The system provides highly accurate classification for four directions of eye movement and has achieved 99.99% accuracy in studies.
- Using simple eye movement, the TCES offers low-cost, high-precision control of external devices/hardware for people with disabilities, surgery robots, warehouse systems, construction tools, and more.
|
9184 |
|
| Parametric Resonance Approach for Efficient, Versatile Acoustic Power Transfer for Implantable/Wearable Devices, Sensing, and Communications |
- New class of transducers utilizes parametric resonance to convert acoustic energy from an ultrasonic source to a sustained electrical signal.
- Technology powers implantable biomedical devices, small wearable sensors, and other wireless charging applications.
- Simple yet robust generation of stable electromechanical frequency combs is also possible in both air and liquid environments using a capacitive micro-resonator array.
|
7635, 9075 |
|
