Life Sciences | Office of Technology Licensing

Available Technologies by Category
Purification of Cell Mixtures Using Molecular Beacons	Purified cardiomyocytes can be used to regenerate damaged cardiac tissue in vivo This method can be used to purify other types of stem cell derivatives It can also be used to develop pure laboratory cell cultures for pharmacologic testing and research	6463
A Screening Method to Detect Ovarian Cancer	Early stage detection Highly accurate Minimally invasive	7028
Microfluidic Platform for Phase Separation of Aqueous Solutions	Efficient workflow- sample removal and analysis can be performed without manual oversight Smaller sample size- less sample volume required alleviating dilution of low concentration solutions that is common in alternative sample preparation workflows Faster process- thermoelectric cooling can induce separation in a matter of seconds with precision and tunability	8247
Compositions & Methods for Using NADH Oxidases	Biocatalysis is used in many industries including food, bioenergy, & pharmaceutical. Recycling cofactors is necessary to control costs of biocatalysis reactions. NADH oxidases convert NADH to NAD+, a major cofactor involved in biocatalysis.	4698
Hydrogel Surfaces for Modulation of Cell Secretory Activity	Multiple formulations – set of hydrogel formulations to control the secretory behavior of cells Customizable – hydrogels can be tailored to exhibit a range of mechanical and biochemical properties: Mechanical properties controlled by length and concentration of polymers, concentration of free radical initiators, curing time Biochemical properties include what peptide, lipid, carbohydrate or other moieties are incorporated into the hydrogel network. Can be formed as flat surfaces or three dimensional matrices	8016
Method for Treatment of Pathologies	Fast - activity is immediate (within 2 hours) Easy to use - applied to nasal sprays or skin patches Safe – less immunogenic	7878
Fluorescence Microscopy with an Ideal sCMOS Camera	Fast – produces fully quantitative sCMOS image restoration up to 100 times faster than the current state-of-the-art Accurate – produces fully quantitative sCMOS image restoration up to two orders of magnitude more accurate than the current state-of-the-art Improved features – allows a broad range of imaging techniques without compromising data reliability	8098
Segmenting Stroke-Like Structures in Images	Computationally efficient User-friendly Operator guidance — correction of errors	4096
Fibrin "Knob" Therapeutics	Simple method Robust production Innate therapeutic potential	4021
Vortex Generators for Prosthetic Heart Valves	Unique- biocompatible and customizable vortex generators Lower-cost- technology of quick molding fabrication Reduced TAT- vortex generators implanted in BMHVs have shown to reduce TAT by greater than 42%	3968
Biomolecular Coating for Implants	Simple, one-step surface modification without chemical cross-linking agents Modification at the time of surgery in the operation room Straight forward sterilization	3967
Annuloplasty Ring & Methods for Tricuspid Valve Repair	Specificity- aligns with specific landmarks only found on the tricuspid annulus Unique- attains an anterior, posterior, and septal segment that conform to the anterior, posterior, and septal sections of the native tricuspid annulus Regulatory- adjustable annuloplasty ring, which facilitates independent control over individual leaflets.	4240
New Methods of Fabrication for Biosensor Arrays	Low manufacturing and operating cost Compatible with multiple standard electrochemical techniques Can be used with CMOS detection chips with multiple chemical detection and/or actuation channels or sites	4231
Piezoelectric Nanowire Based Hearing Aids	Smaller size More power efficient	4222
Fluid Management System for Hemofiltration	Compact- size addresses concern of restricted bed-side space Age-friendly- potential use in any age group, from newborns to adults	4209
Method for Imaging Mass Spectrometry	Precise – Method allows for automatic, precise control of molecule deposition Scalable – Deposition method can be done on large or multiple samples Solvent-Free – Improved imaging quality by eliminating solvent in deposition	4202
Translating Sound into Soft Touch for Haptic Devices	Low cost: Uses components that are less expensive than other high-tech options Better response: Responds more quickly and more refined/granular than existing products with slow and/or coarse responsiveness Enhanced performance: Achieves a silent, smoother, pulse-like response rather than an unpleasant push or buzz	5433
Click Hydrogel for Re-Synostosis Therapy	Provides a novel delivery vehicle for proteins or other factors for correction of craniosynostosis. Spontaneously polymerizes without producing free radicals. Polymerization can safely take place in-vivo. Allows for tunable mechanical properties and compound release kinetics.	5430
Therapeutic Compounds for Prostate Cancer Treatment	Prostate specific: This technology is a targeted approach for androgen receptor malignancies. More effective: It offers a new treatment for tumors that have progressed to the hormone refractory stage. Less toxic: Compounds are highly selective for targeted receptors.	5394
KIDSCRRT – A Device for Continuous Renal Replacement Therapy in Children	Pediatric-friendly- elimination of existing application of adult CRRT devices for pediatric care Improved accuracy- novel pump and control system design complete with offset loop and fluid balance system Versatile- easily integrated with other extracorporeal therapies	5363

Technologies