| BiCMOS Process Integrated Silicon-Germanium Avalanche Photodiode |
- The invention introduces a novel semiconductor photodetector design, leveraging the principle of avalanche multiplication to detect light signals effectively.
- It enables cost-effective high-volume production through the utilization of existing semiconductor foundry processes, bypassing traditional constraints.
- This innovative design supports the integration of a complete optical receiver subsystem onto a single chip, thereby enhancing performance and streamlining production processes.
|
8741 |
|
| Functionalized Nanowires for miRNA-mediated Programming of Naive T Cells |
- Technology Overview: Georgia Tech's functionalized nanowires deliver genetic materials like miRNAs and CRISPR directly to naive T cells, enhancing their therapeutic potential without pre-activation.
- Advantages: This method preserves the naive state of T cells, allowing for better viability and functionality, reduced exhaustion, and delivery of both small and large biomolecules, including lentiviral particles.
- Commercial Applications: The technology can be used in adoptive T cell therapy for cancer and infectious diseases, therapeutic delivery of biomolecules, and as a research tool for immune cell manipulation.
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9341 |
|
| Lymphoid Tissues with Switchable Protein Gradients |
- Technology Overview: Georgia Tech's hydrogel-based immune organoids mimic lymphoid tissue, enabling ex vivo differentiation of B cells and studying immune responses to infections and vaccinations.
- Advantages: This non-invasive method supports long-term B and T cell survival, mimics antibody production processes, and offers insights into diseases like lymphoma.
- Commercial Applications: Useful for drug discovery, clinical research on immune disorders, personalized medicine, and academic studies in immunology.
|
2024-116 |
|
| Engineering Antigen-Specific T Cells for CAR T Cell Therapy via Antigen-Presenting Lipid Nanoparticles |
Technology Overview: Georgia Tech's new CAR T cell therapy uses lipid nanoparticles (LNPs) to program antigen-specific T cells in vivo, potentially reducing costs and production time. Advantages: This approach avoids expensive and time-consuming ex vivo manufacturing, minimizes off-target effects, can adapt to various CAR constructs and cancer types, and promises rapid scaling and reduced costs. Commercial Applications: Applicable to multiple myeloma, CD19+ cancers, and a wide range of other cancers, this technology streamlines CAR T cell therapy manufacturing for faster, more affordable treatments.
|
9386 |
|
| Driving Neural Activity to Rapidly Control Inflammation, Protein, and Gene Expression in the Brain |
- Novel non-invasive method utilizing neural activity to swiftly control inflammation, protein, and gene expression in the brain.
- The technology enables rapid and precise modulation of brain functions, potentially revolutionizing treatment for various neurological conditions.
- Commercial applications include treating Alzheimer's, schizophrenia, autism, epilepsy, and more, offering faster, non-invasive, and targeted therapeutic options.
|
7773 |
|
| Lipid Nanoparticle-Mediated Delivery of mRNA Encoded Synthetic Antigens for CAR T Cell Therapy |
Georgia Tech's novel CAR T cell therapy uses lipid nanoparticles (LNPs) to deliver mRNA-encoded synthetic antigens, improving targeting of solid tumors and reducing off-target effects. The technology ensures efficient mRNA delivery, prompting tumor cells to express unique antigens, enhancing immune recognition and destruction of cancer cells. This approach broadens CAR T cell therapy applicability, allows repeat dosing, and minimizes off-tumor toxicity, offering significant advantages over traditional methods.
|
9385 |
|
| Organic Molecules with Delayed Fluorescence for Human-Centric Lighting and Radiation Detectors |
- Innovative light converter tech mimics natural daylight using organic molecules with delayed fluorescence, surpassing current solutions.
- The technology addresses health issues caused by artificial lighting, offering stable, energy-efficient human-centric lighting.
- It has versatile applications include indoor lighting, therapy for mood disorders, and smart lighting systems.
|
2024-080 |
|
| Controlling the Solubility and Electrical Conductivity of Organic Semiconductor Films by Reversible Doping |
- This innovation introduces a novel approach for achieving precise p-type doping and reversible solubility control in organic semiconductor layers, thereby enhancing their conductivity and stability.
- It provides solution processability and minimal dopant diffusion, leading to improved performance and versatility for a wide range of electronic devices.
- This technology finds applications in printed electronics, organic solar cells, LEDs, transistors, and sensors, facilitating the production of thin, flexible components with enduring performance.
|
7017 |
|
| High Sensitivity Stable Sensors and Methods for Manufacturing |
- This technology introduces dual-gate sensors, separating sensing and amplifying functions for unparalleled stability and sensitivity.
- The innovation addresses limitations of single-gate sensors, providing high sensitivity, low-voltage operation, and compatibility with diverse substrates.
- Applications include wearables, IoT, environmental monitoring, with cost-effective large-scale production.
|
7789 |
|
| Derivatives of Naphthalene Diimides for Organic Electronics |
- This technology utilizes derivatives of naphthalene diimides (NDI) to enhance electron charge mobility in organic electronics, resulting in superior performance in devices like OLEDs and OPVs.
- Key benefits include high thermal, chemical, and photochemical stability of the materials, along with significant improvements in electron affinities and charge-carrier mobility, enabling efficient OFET operation and increased air stability.
- The derivatives have broad commercial applications in fields such as Organic Field-Effect Transistors (OFETs), flexible electronics, Organic Photovoltaic Cells (OPVs), and Organic Light Emitting Diodes (OLEDs).
|
6129 |
|
| Acousto-Optical Sensors for MRI Safety Evaluation |
- The invention is an acousto-optical sensor that can measure the SAR (specific absorption rate) in its environment through temperature and the radio frequency (RF) field.
- The innovation can be used to improve patient safety during MRI scans and to ensure MRI-compatibility for medical implants.
- The solution is more compact and flexible than market alternatives
|
7953 |
|
| mmWave Reconfigurable and Miniature On-Chip Filter Based on Vanadium Dioxide |
- VO2-based combline electromagnetic filter dynamically modulates millimeter wave 5G/6G passband frequencies above 30 GHz using phase-change properties to adjust transmission line lengths with heat.
- Compact on-chip technology streamlines control, accommodates complex shapes and multiple bands, and minimizes insertion loss, addressing spatial, acoustic wave filtering, and efficiency challenges in mmWave arrays.
- Designed for 5G and 6G networks, it enables flexible band switching above 30 GHz, addressing key technical challenges and supporting high-performance telecommunications demands.
|
9470 |
|
| Nanocomposite Film for Volatile Organic Compound Sensing |
- The invention is a new type of chemoresistor capable of sensing volatile organic compounds (VOCs).
- The chemoresistor is comprised of a conductive nanoparticle surrounded by a polymer matrix which allows for the chemoresistor’s
resistance, sensitivity, and target VOC to be adjusted. - The nanocomposite can be placed on electrodes through drop casting, dip coating, and painting, which provides a cheap, simple and sensitive sensor ideal for fieldwork.
|
8695 |
|
| Novel Hydrogels for Encapsulation, Vascularization, and Transplantation of Cells |
- This hydrolytically degradable poly(ethylene glycol) (PEG) hydrogel leverages ester linkages combined at various ratios with non-degradable macromers to enable tunable degradation kinetics.
- Potential applications include controlled release and delivery of drugs or proteins as well as cell encapsulation. It can also be used as a delivery vehicle and adhesive for cells in transplantation settings.
- These innovative hydrogels allow for rapid hydrolytic cleavage in vivo but remain stable in vitro for weeks at neural pH 7 to support regenerative medicine techniques.
|
9019 |
|
| An Improved Lattice-Reduction-Aided K-best Algorithm for Low Complexity and High Performance Communications |
- The invention is a more efficient, less complex version of the LR-aided K-best algorithm as it achieves the same performance as existing algorithms and can perform more computations in less time.
- The algorithm can be applied to any device using the next generation of wireless communication including home networks, cellular systems, and wireless networks.
- The new innovation allows for lower complexity operations, higher system throughput, and a better scalability.
|
6193 |
|
| Composite Hybrid Electrode Material Composed of Alumina, Titania, and Carbon Nanotubes |
- The invention is a new composite electrode material designed for use in supercapacitors.
- The innovation is composed of a hybrid composite material with a thin coating of alumina and titania which allows energy storage systems to have increased energy density, power density, and cycle life.
- The new composite hybrid electrode is fit for use in renewable energy systems, consumer electronics, aerospace and defense, and can provide a more efficient solution.
|
9247 |
|
| Recyclable Organic Solar Cells On Substrates Comprising Cellulose Nanocrystals (CNC) |
- The novel invention utilizes cellulose nanocrystals to create efficient organic solar cells with substrates that are renewable and exhibit strong mechanical and optical properties, achieving a high power conversion efficiency.
- The solution offers an environmentally friendly alternative to traditional silicon-based solar panels by being flexible, low-cost, biodegradable, and easily recyclable at room temperature.
- The innovation is suitable for commercial uses in low-cost electronics, biodegradable printed electronics, wearables, IoT applications, and sustainable building designs.
|
6304 |
|
| Systems and Methods for SmallSat Propellant Positioning |
- The technology provides a way to reliably and efficiently control saturated, or boiling, propellants compared to existing technology.
- The technology can easily be scaled up and applied to different liquids and architectures.
- Significantly enhances the reliability and efficiency of current positioning methods.
|
9165 |
|
| Taskr: Fast and Easy Mobilization of Spot Tasks in Web-based Enterprise Applications |
- The invention is a new, do-it-yourself mobilization solution that users of any skill level can rely on to mobilize their spot tasks.
- Taskr uses remote computing to achieve code-less mobilization, which allows for flexible movable delivery, where users can execute their spot tasks through platforms like Twitter or Email.
- The new innovation empowers users to drive mobilization efforts themselves by limiting coding skills needed for development of mobile apps and mobilizes spot tasks to execute them through various mobile modalities such as app, Twitter DM, text, email etc.
|
7781 |
|
| An Approach to Human-Robot Collaborative Drilling & Fastening in Aerospace Final Assembly |
- The invention is a new, collaborative, and adaptive robot-based approach to complete drilling and fastening tasks autonomously in an adaptable, unstructured environments using an expert demonstrator and human operator.
- The human trains the robot to autonomously complete tasks by defining its environment and demonstrating how to locate, classify, and insert fasteners into a fuselage using a camera and 3D sensor that surveys the area.
- While the system starts with no information, it can use online and offline learning techniques to develop a data bank of information to utilize throughout the insertion process.
|
8805 |
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