Medical Devices | Office of Technology Licensing

Available Technologies by Category
Automated Medical Image Interpretation for Tissue Segmentation	Increased accuracy: Computer processing removes the need to manually interpret boundaries Fast: The algorithm is extremely rapid, repeatable, and accurate Versatile: Programs can be implemented in assembly or machine language	5107
Devices, Systems, and Methods for Excavating Cancer Cells	Tumors are able to migrate on manufactured fibers or films instead of healthy brain tissue Minimally invasive- the device can be deployed directly or using a catheter The device is size and shape variable- films can range from nano- to micron- scale	5057
BrainBraille	Increased information bandwidth and speed for BCI devices Rapid learning of motions and associated meanings Enhanced accuracy	8088
Lab-on-a-Headset Ocular Monitoring Device	Low cost Monitor both eyes simultaneously Can be remotely configured	7814
Nanoparticle Modulation of Thrombus Formation	Selective: Operates only in high shear blood flow as in a stenosis Improved Safety: Reduces the risk of bleeding complications from slow bleeds	7466
PROGNOS: A Web-based Tool for Designing Engineered Nucleases	Algorithm specifically prepared to search entire genomes to identify off-target cleavage sites and design optimal primers for TALENs and ZFNs Available as a simple, user-friendly web-based tool; no extraordinary bioinformatics or biochemical skill required Capable of analyzing TALEN and ZFN sequences targeting human, rat, mouse, zebrafish, arabidopsis, yeast, D melanogaster,	6047, 6058
Ultrasound Methods for Brain Imaging and Therapy	Cost efficient – fast localization, characterization, and control minimize costs Does not require MRI – high-resolution mapping eliminates need for MRI imaging Fast operation – operation can be performed in minutes	8035
High-Precision Microphone for Body-Worn Devices	Wearable small form-factor (micro-chip technology) Increased sensitivity (micro-gravity sensitivity) Large bandwidth (DC to 10kHz) and wide dynamic range (120dB)	7891
In-Vitro Human Bone Marrow-on-a-Chip	Comprehensive – Reconstructs the three environments of bone marrow, current technologies reconstruct two Quick – Does not require lengthy implantation period within an animal model Personalized – Allows for patient specific drug screening bone marrow tests	7883
Multi-Wavelength Microscopy	Groundbreaking - First noninvasive method of assessing the total cell content of a blood bag without breaching the bag and potentially damaging the contents or compromising manufacturing Cheaper - Laser scanning multi-photon microscopy is 5 to 10 times more expensive Improved Imaging – Consistent cross-section of the cells and reduced blurriness	7862
Fabrication Approach to Impart Anti-Wetting Properties	Does not employ particles to control wetting Approach can be used to modify any material surface Cost-effective	7826
Pulse Width Modulated Periodic Backflush	Cheaper – Extends the usable lifespan of filters More Efficient – Improves recovery percentage by an average of 8.4-fold Versatile – Can be applied to both biological and non-biological systems	7793
Short Distance Gait Pace Meter	Accessible – Large-one-touch buttons, large results font, audible and visible sensor cues Inexpensive – Device components low-cost, installation standard wall-mount Convenient – As simple as recording weight or height: Press a button, walk, record speed.	7783
Glucose Regulation Via Electrical Stimulation Of Nerves	Needle-free blood glucose control. Potential to either eliminate or decrease use of blood glucose control medications. First demonstrated use of electrical stimulation to inhibit nerve activity to cause a decrease in measured blood glucose levels	6745
Sampling Interstitial Fluid Using Microneedle Patches	Novel biomarkers – access biomarkers found only in ISF Continuous monitoring – lack of clotting allows continuous ISF collection Minimally invasive – no hypodermic needles or large instrumentation needed	7766
Lithography-Free Nanowire Transistors	Scalable – Eliminating the cost and time associated with top-down patterning enables large-scale manufacturing High Performance – Achieves switching speeds well beyond 1 GHz at supply voltages near 0.5 V Adaptable – Device dimensions can be readily scaled as transistor fabrication techniques advance	7737
Wearable Technology for Joint Health Assessment	Sensitive bio-markers of knee healing process Can be used outside of clinical settings Provides quantitative measurements as opposed to qualitative ones	7000
Wearable Technology for Cardiovascular Activity	Non-invasive measure of cardiac function through wearable ballistocardiography Regular measurements of systolic time intervals during normal daily activities Could be used in harsh environmental conditions including underwater	6714
Chemotaxis Bacterial Cell Separation and Preconcentration	Ease-to-use – Sensor design is simple and device is self-powered Versatile – Allows detection of: NOx, SOx, H2S, CH4, CO, CO2, H2O, HCL, NH3, PH3, toluene, and mercaptons Reliable – Design allows analysis with low power consumption at high temperatures	6535
Ribonucleotide-Capture Method	Enables the mapping of precise-genome wide positions of rNMPs incorporated in genomic DNA Results in sensitive and specific identification and mapping of rNMPs Could be used for further understanding of the biological implication and consequences of rNMP incorporation in DNA	6522

Technologies