Biological | Office of Technology Licensing

Available Technologies by Category
Piezoelectric Nanowire Based Hearing Aids	Smaller size More power efficient	4222
Eliminating Phase Separation Issues	Phase separation is eliminated Growth process is faster Processing temperatures are lower and over a wider range	5459
Alveolar Breath Separation and Collection Device	Simple: this device has fewer components than prior devices Inexpensive: this device is less expensive than previous devices due to its simpler design	4734
Method for Packaging Advanced Sensors and Electronics	High volume — device can be used for simultaneous sensing of thousands of proteins or nucleic acid sequences Cheaper — utilizes low cost wafer-scale semiconductor manufacturing technologies Versatile — can be used for many chemical and biochemical sensors	4514
Fluorescent Nanoprobes for Live-Cell RNA Imaging	Sensitive — can image single molecules with multiple emission wavelengths Fast — probe is multivalent and bind to RNA in less than 10 minutes Low cost — the alternative dual-label probes are more expensive	4513
Carbon Nanotube Electrode Array for Neural Prosthetics	Densely packed CNT arrays allow for better bio-incorporation, prevention of glial scarring, chronic inflammation, and neuronal cell loss Readily functionalized to promote neuronal growth and tissue-electrode adhesion, enhancing electrode performance and quality of read-out signals Inherent mechanical stiffness enhances the rigidity of adjacent CNTs preventing buckling as in other high-aspect probe systems.	4434
Reduced Cyanine Dyes	Simple Synthesis - Easy one-step synthesis from commercially available cyanine dyes Dependable - Exceptional sensitivity Versatile - High stability and wide range wavelength tunability	4430
Scatter Correction for Cone-beam CT in Radiation Therapy	Does not modify either the hardware or the imaging protocols of the clinical system Effectively reduces the scatter signals in the CBCTY scan, and improves image quality Does not require an increase in the dose to the patients	5135
Method and Detection System for Film Thin Waveguides	Enables label free detection of target compounds Thin-film	3600
Lab-on-a-Headset Ocular Monitoring Device	Low cost Monitor both eyes simultaneously Can be remotely configured	7814
Surface Electrode Ion Trap for Cellular Analysis	Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields Enables sorting of cells by optical, chemical, and/or physical properties Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time	6970
High Throughput Spectrometer	Low cost – decrease in the number of components decreases cost Compact – decrease in the number of components decreases size High resolution – improvements in hologram recording maintain high resolutions	3548
Integrated Force Sensing for Probe Microscopy	Optimization of the optical detection sensitivity in air or liquid Mini AFM configuration able to form images in very small volumes Multi-tip nanosensors with simultaneous, multifunctional capabilities	3527
Ultrasound Methods for Brain Imaging and Therapy	Cost efficient – fast localization, characterization, and control minimize costs Does not require MRI – high-resolution mapping eliminates need for MRI imaging Fast operation – operation can be performed in minutes	8035
Smart Petri Chip: Electronic-Photonic Cellular Sensing Platform	Large-scale throughput, real-time cellular monitoring, and re- usability with no contamination Easily and inexpensively replaced Modules can be designed for various functions	6864
High-Precision Microphone for Body-Worn Devices	Wearable small form-factor (micro-chip technology) Increased sensitivity (micro-gravity sensitivity) Large bandwidth (DC to 10kHz) and wide dynamic range (120dB)	7891
Multi-Wavelength Microscopy	Groundbreaking - First noninvasive method of assessing the total cell content of a blood bag without breaching the bag and potentially damaging the contents or compromising manufacturing Cheaper - Laser scanning multi-photon microscopy is 5 to 10 times more expensive Improved Imaging – Consistent cross-section of the cells and reduced blurriness	7862
Facile Synthesis of Ultrathin Silver Nanowires	Produces Ag nanowires less than 20 nm in diameter, with high aspect ratios (over 1000), and in high yield (>85%) One pot, quick (< 35 min) synthetic process that is performed under ambient pressure Great mechanical flexibility and can be bent at acute angles without breaking	6791
GPCR-Based Biosensors for Medium-Chain Fatty Acids	Innovative – first medium-chain fatty acid biosensor Cost Saving – enables more rapid production Diverse applications – applications that require different dynamic and linear ranges	6767
Glucose Regulation Via Electrical Stimulation Of Nerves	Needle-free blood glucose control. Potential to either eliminate or decrease use of blood glucose control medications. First demonstrated use of electrical stimulation to inhibit nerve activity to cause a decrease in measured blood glucose levels	6745

Technologies