Medical Devices | Office of Technology Licensing

Available Technologies by Category
Replaceable Heart Valve Prosthesis	Repeatable- method may be repeated multiple times Versatile- mechanism may substitute more than one valve Lower-cost	3692
Method for Minimally Invasive Heart Valve Procedures	Minimally invasive: heart valve repair system breakdown allows for a smoother process Futuristic: eliminates the need for cardiopulmonary bypass Reduced risk: intends a lower mortality rate during procedure	4483
Core-Shell Nanogel Cellular Delivery Vehicles	Delivery of a broad range of various materials to cells Higher payloads and faster and more sustained RNA interference than non-targeted commercial siRNA delivery vehicle Less toxic than commercial liposomal formulations	4480
Method to Control the Annular Septal-Lateral Diameter of a Valve	Minimally invasive- tools for SLAC deployed endovascularly, percutaneously, or thorocoscopically through a catheter Effective- reduces the septal-lateral diameter on the mitral valve Biocompatible- provides an anchoring system for anchoring a minimally invasively deployed annuloplasty ring	3690
Carbon Nanotube Electrode Array for Neural Prosthetics	Densely packed CNT arrays allow for better bio-incorporation, prevention of glial scarring, chronic inflammation, and neuronal cell loss Readily functionalized to promote neuronal growth and tissue-electrode adhesion, enhancing electrode performance and quality of read-out signals Inherent mechanical stiffness enhances the rigidity of adjacent CNTs preventing buckling as in other high-aspect probe systems.	4434
Reduced Cyanine Dyes	Simple Synthesis - Easy one-step synthesis from commercially available cyanine dyes Dependable - Exceptional sensitivity Versatile - High stability and wide range wavelength tunability	4430
Scatter Correction for Cone-beam CT in Radiation Therapy	Does not modify either the hardware or the imaging protocols of the clinical system Effectively reduces the scatter signals in the CBCTY scan, and improves image quality Does not require an increase in the dose to the patients	5135
A Biodegradable Polymer for Medical Applications	Adaptive and applicable – mechanical properties can be tailored to the desired medical application Controlled biodegradation- biodegradation profile is easily adjustable	5121
Microneedle Coating	Alternative method for hypodermic needles Coating uniformity Spatial control on coating length	3526
Automated Medical Image Interpretation for Tissue Segmentation	Increased accuracy: Computer processing removes the need to manually interpret boundaries Fast: The algorithm is extremely rapid, repeatable, and accurate Versatile: Programs can be implemented in assembly or machine language	5107
Devices, Systems, and Methods for Excavating Cancer Cells	Tumors are able to migrate on manufactured fibers or films instead of healthy brain tissue Minimally invasive- the device can be deployed directly or using a catheter The device is size and shape variable- films can range from nano- to micron- scale	5057
BrainBraille	Increased information bandwidth and speed for BCI devices Rapid learning of motions and associated meanings Enhanced accuracy	8088
Lab-on-a-Headset Ocular Monitoring Device	Low cost Monitor both eyes simultaneously Can be remotely configured	7814
Nanoparticle Modulation of Thrombus Formation	Selective: Operates only in high shear blood flow as in a stenosis Improved Safety: Reduces the risk of bleeding complications from slow bleeds	7466
PROGNOS: A Web-based Tool for Designing Engineered Nucleases	Algorithm specifically prepared to search entire genomes to identify off-target cleavage sites and design optimal primers for TALENs and ZFNs Available as a simple, user-friendly web-based tool; no extraordinary bioinformatics or biochemical skill required Capable of analyzing TALEN and ZFN sequences targeting human, rat, mouse, zebrafish, arabidopsis, yeast, D melanogaster,	6047, 6058
Ultrasound Methods for Brain Imaging and Therapy	Cost efficient – fast localization, characterization, and control minimize costs Does not require MRI – high-resolution mapping eliminates need for MRI imaging Fast operation – operation can be performed in minutes	8035
High-Precision Microphone for Body-Worn Devices	Wearable small form-factor (micro-chip technology) Increased sensitivity (micro-gravity sensitivity) Large bandwidth (DC to 10kHz) and wide dynamic range (120dB)	7891
In-Vitro Human Bone Marrow-on-a-Chip	Comprehensive – Reconstructs the three environments of bone marrow, current technologies reconstruct two Quick – Does not require lengthy implantation period within an animal model Personalized – Allows for patient specific drug screening bone marrow tests	7883
Multi-Wavelength Microscopy	Groundbreaking - First noninvasive method of assessing the total cell content of a blood bag without breaching the bag and potentially damaging the contents or compromising manufacturing Cheaper - Laser scanning multi-photon microscopy is 5 to 10 times more expensive Improved Imaging – Consistent cross-section of the cells and reduced blurriness	7862
Fabrication Approach to Impart Anti-Wetting Properties	Does not employ particles to control wetting Approach can be used to modify any material surface Cost-effective	7826

Technologies