Life Sciences | Office of Technology Licensing

Available Technologies by Category
Interfering RNA Production and Delivery Using Virus-Like Particles	Inexpensive, rapid, adaptable, and reliable in vivo system for sequestering and packaging of iRNAs Flexible, for long or short, single-stranded or double-stranded iRNA of any sequence Efficiently delivers iRNA to biological targets; VLP-iRNAs are readily taken up by many cell types	6427
Method for Intracochlear and Vestibular Magnetic Stimulation	Provides hearing- magnetic fields couple with auditory neurons to produce excitation perceived by the brain was a sound signal Better sound quality- more precise frequency resolution produces better sound quality More reliable signal and decreased sound quality degradation- intervening tissues between array and auditory neurons are no longer a carrier for signals, which will prevent attenuation signal interference	7485
Method for Clinical T-Cell Expansion	Higher cell densities Protection from high shear production environments Reduced initial and operating cost	7434
Antifolate Compound as Multi-Drug Resistant Pathogens	Novel structure with high binding affinity for DHFR Demonstrated growth inhibition of numerous pathogens Demonstrated antibacterial activity for mulit-drug resistant strains of E. coli, methicillin-resistant S. aureus (MRSA), vancomycin-resistant E. faecalis & antifungal activity against amphotericin–resistant Candida albicans	6296
3D Printed Device for Tumor Cell Diagnostics	Minimally invasive – potentially eliminates the need for invasive serial biopsies Cheaper – simple manufacturing process Disposable - size and materials allow for easy disposal	7346
Foot GO: The Foot Granular Orthosis	Customizable: Can easily adjust fit and stiffness Simpler: Has potential to simplify the foot orthosis manufacturing process Re-conformable: Custom fit and stiffness can be readjusted multiple times for changing needs over time	7338
Magnesium Composites for Biomedical Implant Applications	Biodegradable – Healing process is not compromised by a permanent implant device High Strength – Mechanical properties match those of the natural skeletal structure Reliable – Decreases failure during or after installation	6070
Small Molecule Binders of a Human Peptide for Therapeutic Use	First discovery of small-molecules binding to the central catalytic domain of NGly1 Could be used to treat the inherited genetic disorder resulting from NGly1 deficiency	7306
Neuromodulation of Vagal Stimulation	Enhances anti-inflammatory effects of vagus nerve stimulation Pairs electrical stimulation with kilohertz electrical stimulation nerve block to achieve directional stimulation Quick, reliable anti-inflammatory clinical effects	7275
Therapeutic Protein Nanoparticles	Low cost and effective production method Maintains protein structure and enzymatic activity and maximizes the amount of protein to be delivered Preserves bioactivity	5979
Medical Tubing Solution for Bacteria Prevention	Prevent various infections currently impacting patients due to bacteria formation on medical tubes. Solution that can be utilized with existing medical tubes. Does not leach any materials from the tubing surface.	7274
Prosthetic Anterior Cruciate Ligament	Simpler - Simplifies the operation Safer - Prevents unnecessary damage and morbidity at a donor site Readily available - Obviate need for harvest procedure	5856
Surface Nanomodification by Microwave Hydrothermal Treatments	Cost and Energy efficient- requires shorter times of surface modification with a lower concentration of solvents Less hazardous- lower concentrations of solvents decrease the negative environmental impact Versatile- though primarily related to biotechnology, this method can be applied in any industry requiring surface modification	5784
X-Ray Compton Scatter Imaging on Volumetric CT Systems	Reduces radiation exposure in conventional imaging systems Enhances data acquired from VCT, CT, and X-ray imaging Applied to a wide range of VCT systems	5730
Multiplexed Analysis of Cells for Cancer Research	Enables the evaluation of cell properties in a biomimetic three-dimensional microenvironment Mnimal disruption of cell-cell and cell-material interactions Multiplies the number of variables that can be analyzed without significantly increasing the time of analysis	7236
Polymer Wrapping of Single Wall Carbon Nanotubes	Scalable – process can be easily scaled up to enable commercial applications Flexible – PMMA wrap can be applied through a variety of processing conditions Removable – helical wrap allows PMMA to be removed without damaging nanotube	7213
Injection Device for Eye Disease	Safer: Simplifies delivery and lowers the risk of complications Easier: Device can be operated by a non-surgically trained individual using only a single hand Increased Bio-availability: Less drug needed due to injection efficiency	7193
Sutures with Porous Sheaths for Drug Delivery	Accelerated wound healing and tissue regeneration through drug-eluting sutures Increased drug loading and sustained drug delivery due to the interconnected porosity feature of the sutures Release of cytokines, extracellular matrix proteins, anti-inflammatory, anti-microbial, and pain management drugs to injury site	7164
Method to Enrich Glyco-Peptides & Proteins for Analysis	More effective - enrichment of glycoproteins and glycopeptides in complex biological samples, especially low-abundance ones Reversible binding - for intact glycoprotein and glycopeptide analysis	7139
Fog-Free GTE Ventilated Face Mask	Unique- fog-free patient eye-contact Non-invasive- reduced stress in extended medical staff contact with patients Simple- economical and durable	7138

Technologies