The Marcus Center for Therapeutic Cell Characterization and Manufacturing at Georgia Tech is the first research center in the United States to focus on creating the next generation of manufacturing technology to produce large volumes of living cells consistently and at high quality for effective and affordable cell-based disease therapies.
The Marcus Center houses the National Science Foundation (NSF) Engineering Research Center for Cell Manufacturing Technologies (CMaT), led by Georgia Tech and the Georgia Research Alliance. In addition to developing new tools and technologies, CMaT focuses on standards for biomedical research that will vastly improve the reproducibility of therapies and their dissemination across stakeholders.
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The Marcus Center is a “sandbox” for collaboration among engineers, clinicians, and industry to develop and validate new scalable manufacturing processes for cell therapies under GMP (Good Manufacturing Process) conditions that lead to regulatory approval. It is designed to help researchers and industry translate emerging cell therapies to clinical practice. Efforts underway include:
- Understanding cell quality
- Development of scalable processes
- Chip-based disease models for safety and efficacy testing
- New models for supply-chain optimization and logistics
- Immune modulation
- Tissue biofabrication
- Immunotherapies in cancer as well as infectious and autoimmune diseases
- Regenerative medicine