Cell Manufacturing | Office of Technology Licensing

All-Electronic Immunophenotyping Device for Point-of-Care Testing	Convenient: Provides an all-electronic immunophenotyping process with straightforward equipment and techniques Low cost: Performs sophisticated, multistep analyses in a system that is affordable enough for point-of-care settings Flexible: Allows for the easy immobilization of multiple antibodies in the device—a shortcoming of current systems	Cell Manufacturing
Disposable Impedance Biosensor for Cell Manufacturing	Multi-point measurements- provide tempo-spatial profiles of culture attributes and can print a wide range of conductive and insulating materials on both rigid and flexible substrates with non-planar surfaces Wireless - collects the signal wirelessly via printed antennas to simplify the integration to different types of existing bioreactor technologies Safe - system does not apply contact, and minimizes any chance of harm or contamination to affect the cell culture	Cell Manufacturing
Surface Electrode Ion Trap for Cellular Analysis	Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields Enables sorting of cells by optical, chemical, and/or physical properties Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time	Cell Manufacturing
New Imaging Tool to Compare Healthy and Diseased Cells	Discrimination between healthy & diseased cell biology Personalized medicine – specific treatment for an individual Diagnosis of a disease prior to symptoms	Cell Manufacturing
Synthetic Nano-Antibodies for Immunotherapy	Cheaper and faster to manufacture- production only involves synthesis of ligands, nanoparticles, and nano-antibodies; it does not involve cell-lines or animal work More effective- better accumulation and penetration is achieved due to the nanoparticle design Better for patients- dosage to achieve therapeutic efficacy is reduced and can lower the price, duration, and frequency of treatment	Cell Manufacturing
3D Printed Device for Tumor Cell Diagnostics	Minimally invasive – potentially eliminates the need for invasive serial biopsies Cheaper – simple manufacturing process Disposable - size and materials allow for easy disposal	Cell Manufacturing
Multiplexed Analysis of Cells for Cancer Research	Enables the evaluation of cell properties in a biomimetic three-dimensional microenvironment Mnimal disruption of cell-cell and cell-material interactions Multiplies the number of variables that can be analyzed without significantly increasing the time of analysis	Cell Manufacturing
Microfluidic Platform for High-Density Cell Delivery	Allows for hundreds of cells to be immobilized on a very small footprint- including non-adherent cells Can analyze cell response at a single-cell resolution Can simultaneously observe cell response and generate chemical cues- allows for observation of immediate cell response	Cell Manufacturing

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