All-Electronic Immunophenotyping Device for Point-of-Care Testing
  • Convenient: Provides an all-electronic immunophenotyping process with straightforward equipment and techniques
  • Low cost: Performs sophisticated, multistep analyses in a system that is affordable enough for point-of-care settings
  • Flexible: Allows for the easy immobilization of multiple antibodies in the device—a shortcoming of current systems
Cell Manufacturing
Disposable Impedance Biosensor for Cell Manufacturing
  • Multi-point measurements- provide tempo-spatial profiles of culture attributes and can print a wide range of conductive and insulating materials on both rigid and flexible substrates with non-planar surfaces
  • Wireless - collects the signal wirelessly via printed antennas to simplify the integration to different types of existing bioreactor technologies
  • Safe - system does not apply contact, and minimizes any chance of harm or contamination to affect the cell culture
Cell Manufacturing
Surface Electrode Ion Trap for Cellular Analysis
  • Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields
  • Enables sorting of cells by optical, chemical, and/or physical properties
  • Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time
Cell Manufacturing
New Imaging Tool to Compare Healthy and Diseased Cells
  • Discrimination between healthy & diseased cell biology
  • Personalized medicine – specific treatment for an individual
  • Diagnosis of a disease prior to symptoms
Cell Manufacturing
Synthetic Nano-Antibodies for Immunotherapy
  • Cheaper and faster to manufacture- production only involves synthesis of ligands, nanoparticles, and nano-antibodies; it does not involve cell-lines or animal work
  • More effective- better accumulation and penetration is achieved due to the nanoparticle design
  • Better for patients- dosage to achieve therapeutic efficacy is reduced and can lower the price, duration, and frequency of treatment
Cell Manufacturing
3D Printed Device for Tumor Cell Diagnostics
  • Minimally invasive – potentially eliminates the need for invasive serial biopsies
  • Cheaper – simple manufacturing process
  • Disposable - size and materials allow for easy disposal
Cell Manufacturing
Multiplexed Analysis of Cells for Cancer Research
  • Enables the evaluation of cell properties in a biomimetic three-dimensional microenvironment
  • Mnimal disruption of cell-cell and cell-material interactions
  • Multiplies the number of variables that can be analyzed without significantly increasing the time of analysis
Cell Manufacturing
Microfluidic Platform for High-Density Cell Delivery
  • Allows for hundreds of cells to be immobilized on a very small footprint- including non-adherent cells
  • Can analyze cell response at a single-cell resolution
  • Can simultaneously observe cell response and generate chemical cues- allows for observation of immediate cell response
Cell Manufacturing