• Multiple formulations – set of hydrogel formulations to control the secretory behavior of cells
• Customizable – hydrogels can be tailored to exhibit a range of mechanical and biochemical properties:
  • Mechanical properties controlled by length and concentration of polymers, concentration of free radical initiators, curing time
  • Biochemical properties include what peptide, lipid, carbohydrate or other moieties are incorporated into the hydrogel network.
  • Can be formed as flat surfaces or three dimensional matrices

• Low manufacturing and operating cost
• Compatible with multiple standard electrochemical techniques
• Can be used with CMOS detection chips with multiple chemical detection and/or actuation channels or sites

• Precise – Method allows for automatic, precise control of molecule deposition
• Scalable – Deposition method can be done on large or multiple samples
• Solvent-Free – Improved imaging quality by eliminating solvent in deposition

• High volume — device can be used for simultaneous sensing of thousands of proteins or nucleic acid sequences
• Cheaper — utilizes low cost wafer-scale semiconductor manufacturing technologies
• Versatile — can be used for many chemical and biochemical sensors

• Sensitive — can image single molecules with multiple emission wavelengths
• Fast — probe is multivalent and bind to RNA in less than 10 minutes
• Low cost — the alternative dual-label probes are more expensive

• Simple Synthesis - Easy one-step synthesis from commercially available cyanine dyes
• Dependable - Exceptional sensitivity
• Versatile - High stability and wide range wavelength tunability

• Can be operated under ambient temperature and pressure
• Higher chemical and spatial resolution than currently exists
• Has the ability to pair mass spectrometry to microscopy

• Simple — does not require difficult or extensive preparation
• Regenerative — provides unique molecular cues similar to early embryogenesis, enabling directing of cell differentiation and tissue morphogenesis
• Compatible and customizable — can be tailored for specific tissue applications by directing the differentiation of the ES cells prior to acellularization

• Can isolate the central region of a diffraction spot from its respective fringes
• Creates ideal diffraction patterns

• More precise — Three orders of magnitude decrease in volume of fluid containment when working with the microscope
• Cost-saving — Allows for the use of less analyte (important for drug companies)

• Low cost
• Monitor both eyes simultaneously
• Can be remotely configured

• Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields
• Enables sorting of cells by optical, chemical, and/or physical properties
• Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time

• Low cost – decrease in the number of components decreases cost
• Compact – decrease in the number of components decreases size
• High resolution – improvements in hologram recording maintain high resolutions

• Optimization of the optical detection sensitivity in air or liquid
• Mini AFM configuration able to form images in very small volumes
• Multi-tip nanosensors with simultaneous, multifunctional capabilities

• Large-scale throughput, real-time cellular monitoring, and re- usability with no contamination
• Easily and inexpensively replaced
• Modules can be designed for various functions

• Comprehensive – Reconstructs the three environments of bone marrow, current technologies reconstruct two
• Quick – Does not require lengthy implantation period within an animal model
• Personalized – Allows for patient specific drug screening bone marrow tests

• Cheaper – Extends the usable lifespan of filters
• More Efficient – Improves recovery percentage by an average of 8.4-fold
• Versatile – Can be applied to both biological and non-biological systems

This technology can be used in the development of yeast-based syntheses of plant alkaloids, or any other biosynthetic pathway that uses 5-hydroxytryptohan or L-DOPA as precursors. It can be used for the synthesis of compound monoterpene indole alkaloids derived from strictosidine (e.g. quinine, camptothecin, ajmalicine, serpentine, vinblastine and vincristine) or benzylisoquinoline alkaloids derived from dopamine (e.g. berberine and morphine).

• Apatamers have unique secondary structure, allowing them to bind with high specificity and affinity to a specific target
• Utilizes intrinsic double stranded DNA break (DSB) and repair system, enabling targeted delivery of exogenous DNA in all eukaryotic cell types
• AGT development could lead to enhancement of gene editing technologies and ultimately disease-targeted therapy

• Enables the mapping of precise-genome wide positions of rNMPs incorporated in genomic DNA
• Results in sensitive and specific identification and mapping of rNMPs
• Could be used for further understanding of the biological implication and consequences of rNMP incorporation in DNA