Available Technologies by Category
A Partial-Hand Prosthesis Simulator
  • Specific: Designed to maintain limb length by placing artificial fingers in positions similar to where they would be in an intact hand performing grasping actions (rather than extending the length of the limb as many prostheses do)
  • User friendly: Features rubber-capped fingertips that may provide a more lifelike representation of grasp and enhance usability
  • Nuanced: Designed to limit tactile sensation and feedback from immobilized fingers, which may allow better evaluation of how the device is functioning for the patient in comparison to an actual prosthesis
8534
Portable Multi-Parameter Cancer Diagnostic Tool
  • Powerful: Simultaneously measures multiple tissue parameters to determine electro-thermo-mechanical properties
  • Disposable: Uses single-use biochip components to eliminate cross-contamination
  • Versatile: Uses a variety of other micromotion-capable actuators and extends to other manufacturing techniques and different length scales
7619
Vest-Style Device Assists Ventilation and Perfusion (V/Q) to Help Prevent Respiratory Failure
  • Powerful: Designed to optimize oxygenation for patients in acute hypoxic respiratory failure
  • Supportive therapy: Non-invasively complements mechanical ventilator support
  • Low cost: Significantly less expensive than technologies that increase oxygenation (e.g., ventilators, oxygen systems)
8529
Novel Polymer Hybrid Improves Stability of Implantable Devices
  • Strong: Provides structural stability and enhanced cellular adhesion for implant materials
  • Biocompatible: Reduces the risk for complications that could arise with the use of chemical components
  • Customizable: Permits easy incorporation of various nanomaterials to fine-tune devices to meet patient needs
8449
Multi-Functional Sparse Phased Arrays for Guiding Focused Ultrasound Therapies
  • Robust: Provides sensitivity of detection down to a single microbubble for FUS-induced microbubble activity
  • Precise: Offers broadband B-mode imaging capabilities to improve workflow and efficacy of FUS-based therapies
  • Scalable: Enables the formation of large CMUT arrays and subarrays with appropriate element spacing
8493
Inverted Organoids for Breast Cancer and Other Invasion Studies
  • Innovative: Serves as a convenient platform for studying the invasive abilities of breast cancer cells
  • Stable: Enables formation of large inverted organoids where the basement membrane forms on the interior surface alongside a breast cell line epithelium
  • Flexible: Allows for long-term studies of at least 25 days due to the robust maintenance of the inverted orientation
8460
Assessment of Soluble Cancer Biomarkers for Focused Ultrasound Therapy
  • Simple: Avoids reliance on magnetic resonance imaging (MRI)-based methods of monitoring and optimizing FUS therapy
  • Safe: Relies on a small amount of fluid collected before/after FUS-targeted drug delivery
  • Robust: Enables a range of new therapeutic interventions for cancerous tumors as well as both delivery and monitoring/optimizing of those therapies
8473
Streamlined Hematology Analysis for Point-of-Care Settings
  • Streamlined: Enables testing in point-of-care settings without complex procedures and specially trained personnel
  • Highly accurate: Offers a spatial resolution higher than current methods due to the shorter wavelength of UV light
  • Cost-effective: Saves on reagents, complex equipment costs, and time-intensive processes without compromising diagnostic quality
8303
Technique Improves Printing Quality for 3D Nanoprinting
  • High-performance: Enables a powerful process for high-throughput 3D printing of micro- and nanoscale structures
  • Efficient: Reduces defects during printing to improve yield and decrease excess printing commonly observed with FP-TPL
  • Improved: Broadens the applicability of FP-TPL to printing of functional micro- and nanoscale structures
8478
Super-Absorbent Polymer (SAP) Beads for Collection of Biofluid Samples
  • Fast: Accommodates preloading of specimen collection tubes and completes absorption of analytical targets within a few minutes of fluid collection
  • Low cost: Employs economical materials and eliminates the need for refrigeration of samples while also lowering the weight of samples for transport
  • Easy to use: Avoids the need for filtration, centrifugation, or pipetting and the associated equipment for such tasks
7907
Airy-beam Tomographic Microscopy for Biological Imaging
  • Streamlined: Offers a scan-free method of obtaining 3D-resolution images
  • Volumetric imaging: Generates and resolves images of tissues and cells in the 3D space  
  • High resolution and image depth: Provides 3D diffraction-limited resolution 
8381
High-Precision Cell Membrane Tracking for Automated Electrophysiology
  • Highly accurate: Overcomes the challenges of tissue interference and movement for precise membrane tracking that can be used for automation
  • Instantaneous: Surpasses earlier attempts at automating this process by effectively identifying and tracking cell boundaries in real time
  • High fidelity: Operates efficiently and precisely even in dynamic, high-interference environments
7467
Ultra-High Resolution Multimodal Imaging System
  • Integrative perspective imaging - topological and chemical imaging of complex biological samples and heterogeneous nanomaterial interfaces with sub-micrometric resolution
  • Improved spatial resolution - system provides chemical imaging resolution of ~ 250 nm and electron microscopy topological resolution of ~ 50 nm.
  • Accuracy in analytics - analysis at the level of a single cell or with subcellular resolution has been seen as a next frontier in innovative approaches to discovery
8300
Guided Injection of Charged Cargo for Intracellular Delivery
  • Novelty – use of an electrically-charged liquid beam of electrospray
  • Improved control – control of action on the scale of single cell/single pores
  • Diversity – arbitrary diverse set of cargo
8275
Water-Soluble Mold for Sample Analysis
  • Inexpensive: difference in materials used from existing practices, lowers manufacturing costs  
  • Universal adoption: no requirement of expensive cleanrooms facilities and associated personnel
  • Environmentally: conscious- non-toxic process eliminates need for organic solvent and waste treatment
8138
Constellation Diagrams to Model Biomolecules’ Electrostatic Properties
  • Low computational cost – reduces algorithm run-time via reduction in complexity of computing molecular electrostatic properties
  • Digitally encoded molecular electrostatic properties – utilizes orthogonal basis functions
  • Visual toolsets- to analyze molecular electrostatic properties and generates 4D plots of molecular electrostatic properties
8245
Storage Media for Determining Optimal Respiratory Treatment
  • Automatically determines optimal radiation therapy treatment phase
  • Enables higher, more effective radiation dosage amounts
  • Minimizes unnecessary radiation to normal surrounding tissues
6926
Purification of Cell Mixtures Using Molecular Beacons
  • Purified cardiomyocytes can be used to regenerate damaged cardiac tissue in vivo
  • This method can be used to purify other types of stem cell derivatives
  • It can also be used to develop pure laboratory cell cultures for pharmacologic testing and research 
6463
A Screening Method to Detect Ovarian Cancer
  • Early stage detection
  • Highly accurate
  • Minimally invasive
7028
Compositions & Methods for Using NADH Oxidases
  • Biocatalysis is used in many industries including food, bioenergy, & pharmaceutical.
  • Recycling cofactors is necessary to control costs of biocatalysis reactions.
  • NADH oxidases convert NADH to NAD+, a major cofactor involved in biocatalysis.
4698