Current methods for isolation CTCs reduces detection rates
The problem with current ex vivo methods for isolating circulating tumor cell (CTC) clusters is their limitation to small blood volumes, which reduces detection rates and prevents comprehensive longitudinal analysis. These limitations hinder the effective study of tumor heterogeneity and metastasis.
This new extracorporeal circulation system overcomes these challenges by enriching CTC clusters from large blood volumes outside the body. This technology enables continuous, detailed screening and analysis of CTC clusters, facilitating in vitro culturing, drug testing, and integration with drug delivery systems for targeted treatment. It significantly improves early cancer detection and treatment by removing metastatic precursors from circulation.
Methods for combating metastasis are improved using large blood volumes
This technology introduces an extracorporeal circulation system that enriches CTC clusters from large blood volumes, overcoming the limitations of current ex vivo methods. By processing blood outside the body and isolating CTC clusters, this system facilitates longitudinal screening and detailed analysis of these clusters, which are critical in understanding and combating metastasis.
- Improving detection rates.
- Offers potential for retarding or preventing metastasis through continuous operation.
- Supports continuous and longitudinal screening.
- Provides capabilities for mechanical, thermal, and UV-based manipulation of isolated cells for research and therapeutic purposes.
- Facilitates downstream functional analysis of CTC clusters.
• In-line dialysis or treatment systems for pathogenic cells in diseases like cancer
• Enhanced detection of circulating tumor cells for early diagnosis and monitoring of cancer.
• Research tools for studying tumor biology, heterogeneity, and developing new cancer treatments.