Available Technologies by Category
A Chip-Scale Linear Ion Trap to Enable Portable Mass Spectrometers
  • Enabling: Can be used in the development of much smaller mass spectrometers than are currently available—from benchtop devices to handheld or even smaller instruments—which would extend their use to applications in which they are not currently cost effective
  • High-performance: Provides better than unit-mass resolution and high detection efficiency, and operates at much higher pressures than larger mass analyzers, as shown during lab-based simulations
  • Multi-modal: Allows for several different modes of operation and enables tandem(MS/MS or MS2) or multi-stage/sequential (MSn) mass spectrometry, greatly improving capability compared with other analyzers
Increasing Medium-Chain Fatty Acid (MCFA) Yield in Bacterial Host with Engineered Enzyme
  • High performance: Increases the yield of MCFAs during chemical and biopolymer synthesis
  • Enabling:  Improves the microbial production of chemicals that require the expression of heterologous enzymes
  • Adaptable:  Potentially applies to methods of engineering other heterologous enzymes to interact with endogenous proteins in order to produce molecules of interest in a bacterial host
Quasi-Melt Processing Technique for Stronger Single-Polymer Composites
  • Highly effective: Facilitates increased fabrication of SPCs using a variety of processing techniques
  • Simpler: Eliminates the need to develop a textile preform, which is necessary during fiber hot compaction processing
  • Flexible: Is compatible with standard high-throughput melt processes for polymers and plastics
A Biomimetic Nose with Machine Learning for Advanced Threat Detection
  • Enhanced chemical detection: Reduces proximity issues and enhances detection
  • Functional in air and liquid mediums: Can detect single or multiple chemical agents even when the medium contains both a liquid and a gas. An attachment makes it possible to use the device in liquid with air monitoring sensors.
  • Continuous improvement: Uses machine learning algorithms to continually improve agent characterization
Tissue-Selective Anticancer Agents
  • Tissue-targeted activity: Appended macrocyclic skeletons provide selective tissue distribution.
  • Potent: HDAC inhibitors display stronger in vivo anticancer activity against solid tumors compared to current technology.
  • Lower toxicity: Mice in preclinical experiments did not exhibit significant weight loss, pointing to potentially lower toxicity of these compounds.
Heat-Responsive Programmable T-Cells
  • Specific: The remote programmable nature of these T-cells allows them to be selectively activated only in the necessary locations.
  • Protective: This focused, genetically engineered immunotherapy is intended to protect patients from the additional harm of the off-target cell death and unnecessary systemic damage that is more common with oncological therapeutics.
  • Non-invasive: With NIR light’s ability to penetrate into multiple layers of biological tissue and be absorbed by AuNRs, this technology removes the need for a light source in the body to trigger the T-cells.
Self-Titrating Bacterial Protease-Activated Prodrug
  • Effective: Activates an internal dosing mechanism such that the magnitude of an infection locally determines the prodrug dose
  • Robust: Increases the stability of the prodrug form by neutralizing the effective charge of the administered antimicrobial peptide
  • Improves safety: Decreases the potential for off-target effects
Scalable, Low-Cost, Inversion-Free Method of Enabling Automated Underside Cell Seeding
  • Convenient: Eliminates the need for inversion procedures, which tend to be tedious, difficult to automate, and prone to failure—especially for 96-well inserts due to their limited culture area
  • Generalizable: Developed for screenings that focus on the air-blood barrier, but can also be  applied to gut, skin, oral mucosa, and other organ systems
  • Scalable: Employs a simple method that is extensible to automated processes for high-throughput drug screenings and pharmacological tests
Rapid Development of SARS-CoV-2 Monoclonal Antibodies
  • Powerful: Demonstrates potential to recognize intact SARS-CoV-2 virions with high affinity
  • Highly efficient: Enables researchers to select pairs of high-affinity antibodies that bind to different receptor sites, maximizing the efficiencies of sandwich-style rapid testing methods
  • Enabling: Furthers the development of neutralizing antibodies that can be used as therapeutic agents, delivered either directly or via mRNA for in situ expression
Real-Time Mobilization of Computer Software Applications
  • Comprehensive: Overcomes speed, traffic, and interface limitations of basic remote computing
  • Resourceful: Allows for seamless function without a high data usage burden
  • Efficient: Applies unique transformation services to accelerate and enhance the user’s mobilized application experiences
AwareSite Proximity Safety Sensing System for Construction and Other Work Sites
  • Improved work safety and efficiency: Not only are accidents prevented when workers and equipment operators are alerted that they are crossing set safety boundaries, their proximity and movement data are also stored in the cloud and can be used to analyze work patterns that could improve safety, work process efficiency, and more.
  • Low-cost and flexible hardware: The system uses inexpensive custom PPU devices but can also be paired with workers’ personal smartphones for connecting to the system.
  • User friendly and reliable: System setup and operation is simple. Beacons use Bluetooth® low-energy technology and can last more than one year without changing batteries.
7970, 7971
Advance Warning System for Improved Safety in Roadway Work Zones
  • Enhanced safety: Rather than relying on impact-activated devices, the system issues real-time warnings as soon as the perimeter is breached, providing more time for workers to react and get to safety.
  • Portable and changeable: The system can be easily moved or adjusted to accommodate changes to the work zone during the day.
  • Smart analytics: Analysis of intrusion data helps pinpoint areas within the work zone that are more susceptible to breaches, enabling more effective and efficient security.
Rapid Mobilization of Essential Enterprise Applications
  • Rapid: Significantly reduces time needed to mobilize an enterprise application as compared to conventional mobilization solutions
  • Cost-efficient: Leverages a cloud-based, codeless platform that saves on both time and budget
  • Flexible: Demonstrates potential to efficiently provide mobile functionality for a wide variety of applications necessary for business operations
Skin-Conformal Wearable Stress Monitor Delivers Greater Precision and Continuous, Wireless Monitoring with Comfort and Flexibility
  • All-in-one: The personal adhesive bandage-like single device platform offers wireless, multi-data sensing by simply mounting it on the skin.
  • Disposable: This wearable device is fully disposable after the use and the measured data can be simply sent to the cloud via a tablet or smartphone app.
  • Compact: The unique, thin design of this bioelectric device is one-sixth the volume of current market offerings—weighing less than 7 g, including its rechargeable battery.
Using Smart Macros to Optimize User Actions on Smartphones
  • Improves user experience: Provides near-desktop level experience for the mobile phone environment
  • Easy to use: Reduces user burden by presenting programmable macros in a simple and user-friendly manner
  • Causes minimum overhead: Does not contain any process that degrades the remote desktop performance because of high requirements for the central processing unit (CPU) or memory
Super Aggregation: Multihoming for Wireless Devices
  • Performance-improving: Improves the aggregate performance of multiple heterogeneous wireless interfaces used simultaneously compared to the performance each could achieve on its own  
  • Proven: Indicates TCP acceleration achieved in wireless data networks when tested on two mobile platforms, including a laptop computer and an Android mobile phone
  • Impactful: Addresses the performance improvement needs of ubiquitous, widely used mobile technologies
Fully Passive, Long-Range Radio-Frequency Identification (RFID) via 5G
  • Large coverage: Provides a unique combination of large angular coverage and turn-on sensitivity in both planar and bent configurations
  • Long range: Demonstrates the potential for RFIDs with practical reading ranges over 1.8 km
  • Scalable: Scales in size to a precise degree, enabling selection of the optimal tradeoff between size and harvested power/reading range
8141, 8439
Smart Webcam Shield Protects Users from Unknown External Digital Intrusion
  • Secure: Offers visual obstruction of the webcam even when remote software attempts to record without triggering the computer’s LED indicator  
  • Reliable: Automates the webcam safeguard for ongoing protection without reliance on user engagement
  • Flexible: Enables two different actuators via the same sensor
Adaptive Broadband Impedance Matching in Ultrasound Front-End Electronics
  • High performance: Improves power transfer and acoustic reflectivity
  • Flexible: Enables multimodal and tunable operation of CMUTs
  • Efficient: Provides optimal matching for co-design of CMUT electronics
Purely Passive Radio-Frequency Identification
  • Powerful: Projected to support energy harvesting sensors at distances over 100 meters from readers and/or radio transmission sources
  • Efficient: Enables conversion of RF energy at higher efficiency and at higher output voltages than current electronic energy harvesting methods
  • Widely applicable: May advance RFID applications in a wide range of fields including computing, sensing, and communication