Available Technologies by Category
“Smart” Feedback-Controlled Bioreactor Platform Enables Consistent High-Yield and High-Quality MSC Products
  • Scaled-down feedback-controlled hollow fiber-based bioreactor enables identifying the critical quality attributes and critical process parameters for high-quantity and high-quality hCT-MSCs for ideal cell growth and efficacy 
  • Provides the controls to maintain optimum conditions and improve expansion yield and cell viability
  • System can be adapted and applied to industrial cell therapy manufacturing and can enable high-yield and high-quality products while minimizing variabilities
Manually Powered Laboratory Mixing Device
  • This manually operated laboratory device mixes and separates solution components at performance levels comparable to existing powered vortexes and centrifuges.
  • The device operates with no external power source, providing labs without access to consistent electrical infrastructure a reliable solution to mixing and separating solution components.
  • This multiuse device is compatible with containers and sample tubes of various sizes and solution amounts.
Novel Silicon Radiation Detector Enabled By Tunnel Oxide Passivating Contact
  • The technology passivates the bottom surface well and suppresses electron recombination near the bottom contact, resulting in low leakage current.
  • Passivating the silicon surface and decreasing hole recombination near the front contact leads to low recombination current density at the surface and low effective contact resistivity.
  • An extremely low J0 for the tunnel oxide passivating contact on both sides yields a higher energy resolution and lower noise level.
High-Precision, Hands-Free Remote Control of Complex Robotic Systems Via Eye Movements
  • This two-camera eye-tracking system (TCES) integrates a commercial eye tracker with machine-learning technology for continuous real-time classification of gaze and eye directions for robotic arm control. 
  • The system provides highly accurate classification for four directions of eye movement and has achieved 99.99% accuracy in studies.
  • Using simple eye movement, the TCES offers low-cost, high-precision control of external devices/hardware for people with disabilities, surgery robots, warehouse systems, construction tools, and more. 
Customized 3D-Printed Bioresorbable Heart Valves
  • Resorbable, patient-specific heart valves offer great flexibility for treating a wider range of conditions and patients than traditionally manufactured heart valves. 
  • Customizable valves potentially decrease complications due to poor fit and the need for reinterventions.
  • Selecting materials for optimal mechanical properties, thermodynamic properties, chemical properties, and surface chemistry and morphology reduces mismatch between device and tissue, potentially improving performance and patient outcomes.
Paper-Based Multi-Well Depletion Enzyme-Linked Immunosorbent Assay (ELISA) Enables Point-of-Care (POC) Testing
  • Paper-based lateral flow assay automatically performs multi-well ELISA testing for POC titer measurements.
  • Simplifies ELISA testing by eliminating the need for centralized laboratories staffed with trained personnel who perform multiple steps in a specific sequence to execute the assay workflow.
  • Transforms a variety of ELISA-based tests into single-use, disposable dipstick tests to be used at the point of care or at home.
Streamlined Combination Analysis by FORECAST Accurately Predicts and Identifies Pending Malware Attacks
  • Automating the combined techniques of memory forensics and symbolic analysis accelerates how fast an enterprise or government becomes aware of the true extent of malware’s capabilities.
  • When countering cyberattacks, FORECAST provides improved accuracy (94%, overall) with its automated analysis, which is crucial to helping cybersecurity efforts to efficiently focus on high-impact solutions.
  • FORECAST has the flexibility to be a valuable incidence response tool, even when malware is fileless since it uses the software’s memory image to accurately predict the program’s capabilities.
Electric Field Treatment Creates Safe, Effective Antimicrobial Surfaces
  • Creates safe, effective antimicrobial surfaces via bacteria inactivation without the use of chemicals
  • Targets cell membranes or capsid, is less likely to induce antimicrobial resistance, and should be effective for antibiotic-resistant bacteria
  • Requires very short electrical pulses to achieve effective bacteria inactivation, potentially leading to better antifouling performance
Parametric Resonance Approach for Efficient, Versatile Acoustic Power Transfer for Implantable/Wearable Devices, Sensing, and Communications
  • New class of transducers utilizes parametric resonance to convert acoustic energy from an ultrasonic source to a sustained electrical signal. 
  • Technology powers implantable biomedical devices, small wearable sensors, and other wireless charging applications.
  • Simple yet robust generation of stable electromechanical frequency combs is also possible in both air and liquid environments using a capacitive micro-resonator array.
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Customizable Smart Charging Solution for Electric Vehicles in Residential Areas
  • This customizable smart charger uses algorithms and a hardware prototype to control electric vehicle charging and optimize benefits to consumers and power grid operators. 
  • Consumers can charge according to their preference (e.g., minimize cost, maximize carbon-free energy usage, minimize charging time, or minimize battery degradation).
  • The smart charger selects charging profiles that delay charging to avoid excessive loads on the power grid.
Chemically Modified Reduced Graphene Oxides (rGOs) Improve Strength and Qualities of Polymer Composites
  • Chemically modifying rGO creates improved dispersibility and miscibility that can be used in polymer processes as a composite reinforcement or coating material.
  • Easily scalable solution chemistry and purification/filtration makes the process economically feasible, resulting in a commercially viable material for many applications.
  • Melt lamination results in a robust conductive coating that is more durable than comparable polymer-based coatings and enables many electronically active device designs.
Artificial Neural Network (ANN) with Unique Input Design that Significantly Reduces Computational Costs of Complex Engineering Systems
  • Neural network’s novel input can utilize first-order schemes and local patches and allows for discontinuities to be reflected accurately and with greater resolution than existing products.
  • This adaptable ANN can be adopted by commercial and scientific research as a stand-alone solution or in conjunction with existing software. 
  • Lower costs for running complex and repetitive computations can be achieved by implementing this neural network with an input system that processes low-cost numerical solution patches arising from two or more converging solutions.
Improved Electrically Driven Temperature Swing Adsorption (ETSA) System for Faster, More Productive Direct Air Capture of Carbon Dioxide
  • This electrically driven temperature swing adsorption (ETSA) system uses sorbent-coated carbon fibers that exhibit Joule heating and rapid temperature swings for improved CO2 direct air capture (DAC).
  • Over ten times faster temperature controls and six times faster CO2 desorption rate in ETSA than temperature swing adsorption (TSA) operation under the same DAC condition
  • The dual-layered structure composed of a Joule heating core and CO2 adsorbing coating layer result in a larger amount of CO2 chemisorption.
Melting Microneedle Patches Extend Drug Delivery Applications, Simplify Manufacturing, and Reduce Costs
  • Melting microneedles enable dispersion of both poorly soluble and water-soluble drugs, which eliminates the need for solvents for improved stabilization and broader applications.
  • Melting microneedles shorten manufacturing and drying time, eliminate the need to maintain a cold chain for storage and transportation, and reduce the ultimate cost of the microneedle patch.
  • The safe suppository bases are inexpensive and enable control of the drug release timing.
Quantitative, Performance-Driven Framework for Optimal Desalination Architectures and Energy Subsystems
  • Incorporate and simultaneously compare attributes of multiple types of both desalting systems and energy subsystems for optimal system architectures
  • Assess parameters that impact overall cost to discover complete architectures that would not have been discoverable using traditional methods.
  • Focus on renewable energy subsystems such as solar, wind, geothermal, hydroelectric, and others to create complete desalination architectures that are cleaner and more water efficient than their conventional counterparts. 
Novel Nanocarriers Strengthen Therapeutic Delivery, Improves Efficacy
  • Greater therapeutic effectiveness is due to the synergistic work of multiple therapeutic agents (hydrophobic/hydrophilic charged) that can be delivered via this dual-loaded biomaterial.
  • The risk of immunotoxicity to a vaccine is reduced because an adjuvant, which can induce the body’s anti-inflammatory immune response, may be loaded and simultaneously delivered with the vaccine. 
  • The novel nanocarrier has broad market application since it can deliver vaccines, gene therapy, small molecule drugs, and even contrast agents.
Automated Bioreactor Sampling System Can Eliminate Cross-Contamination of Samples
  • Automated bioreactor sampling system maintains sample integrity by changing the syringe between samples
  • In addition to savings related to reduced cross-contamination, automated sampling can further lower costs by reducing hands-on time and speeding sampling.
  • Flexible platform can be used with any type of collected sample.
Enhanced Cybersecurity for Networked Motion Control Systems with Somewhat Homomorphic Encryption
  • Increase cybersecurity with expression rewrite rules for encrypted dynamic control schemes that reduce the multiplicative depth of somewhat homomorphic encryption and improve numerical stability. 
  • New approach generates motion commands to servo systems without creating a security hole.  
  • Information decryption and control signal calculation can be performed and executed inside the plant, while all sensitive system information outside of the plant is always encrypted. 
Anodically Coloring Molecular Electrochromics (EC) Improve Contrast, Color, and Transitions
  • True black-to-clear transitions with high contrast and color tuning are now possible with anodically coloring electrochromics.
  • Broad absorption supports color mixing and color tunability in the charged state, and color tuning is enabled by manipulating the oscillator strengths of radical cation transitions.  
  • Energy required for practical electrochromic applications is effectively decreased by much lower oxidative potentials, as compared to their corresponding polyamides.
Cost-Effective Hydra Method Monitors DRAM Memory in Computers
  • Hydra combines the best of SRAM-tracking (low performance overhead) and DRAM-tracking (low SRAM overhead and flexibility) to produce Row-Hammer (RH) mitigation that is effective at ultra-low thresholds.
  • Proven results in mitigating the increasing RH security vulnerability issue, Hydra offers a low-cost solution that is widely applicable to all computer systems that use DRAM—over one billion devices. 
  • Hydra is a hybrid tracker that successfully mitigates RH security issues and does not compromise the functionality of the computer system.