Available Technologies by Category
Foot Ankle Orthotic (FAO) Delivers Real-Time Portable, Discreet Haptic Feedback for Patients and Athletes
  • Providing patients with discreet notifications of real-time plantar pressure to improve rehabilitation of foot-ankle injuries between clinical visits can reduce risk of injury strain and minimize long-term damage.
  • Athletes from various sports (e.g., tennis, football, basketball) could prioritize injury prevention during practice and games because of the discreet haptic notifications that bring attention to foot planting techniques via pressure monitoring.
  • The benefits of measuring plantar pressure from the four zones of this device’s insole (heel, toes, medial, and lateral) extend beyond foot-ankle injuries and can be key to diabetic pressure wound prevention as well as knee osteoarthritis therapy.
8944
Portable, Reusable, Micropower Radiation Monitors Provide Real-Time Assessment of Radiation Risk
  • Innovative radiation detection system provides real-time, on-demand, micropower detection in a versatile design.
  • The device materials offer higher conductivity (mobility) than silicon, resulting in reduced power needs (i.e., requiring power only during read-out).
  • Selection and layering of channel and gate materials enables tuning devices for different radiation types.
8084
Plasma-Activated Catalytic Air Purifier Cleans Enclosed Spaces
  • This plasma-activated catalytic air purifier can be used to clean enclosed spaces, such as aircraft, hospitals, and classrooms, while mitigating hazardous gas-phase byproducts. 
  • The air purifier can be used synergistically with UV diode lasers and UV lamps, providing additional contaminant destruction pathways while lowering the potential for dielectric breakdown and plasma formation.
  • This comprehensive technology is effective for germicide and sterilization activities as well as for hydroxyl-radical production and ozone removal in a wide variety of indoor environments.
8536
Custom-Fit Reusable Respiratory Protective Device (RPD) with Continuous Fit Monitoring Improves Comfort and Protection
  • Vastly improves comfort and protection while bringing peace of mind to wearers through a custom fit and continuous monitoring
  • Reduces pressure injuries caused by extended RPD use through both a customized fit and alerts to the wearer when the RPD should be adjusted or removed
  • Minimizes exposures to workplace hazards by immediately detecting leakage during RPD use and alerting the wearer to adjust the device
8876, 9089, 9090, 9091
Deployable Critical Active Learning (DECAL) System Offers Better Characterization for Improved Diagnostics and Imaging
  • The deployable critical active learning (DECAL) system’s bi-modal interface enables better characterization with large training sets that generate more accurate output for higher precision.
  • The algorithm used during the initialization period creates a framework that can be expanded and generalized to any data method and application.
  •  The DECAL algorithm samples uniquely important, unlabeled data to aid existing active learning systems in generalizing more quickly, providing faster diagnosis statistics.
9099
Sustained Lymphatic Drug Delivery System Potentially Improves Efficacy and Safety of Immunotherapy and Targeted Therapies
  • This sustained lymphatic drug delivery system guides therapeutics and imaging agents to the injection site, lymphatic vessels, and lymph nodes. 
  • Sustained lymphatic delivery enables lower dosing and fewer administrations to potentially improve therapeutic response while reducing adverse effects and costs.
  • The simplicity of a vaccine-like, sustained drug release injection allows use at less expensive community health centers.
8637
Manually Powered Laboratory Mixing Device
  • This manually operated laboratory device mixes and separates solution components at performance levels comparable to existing powered vortexes and centrifuges.
  • The device operates with no external power source, providing labs without access to consistent electrical infrastructure a reliable solution to mixing and separating solution components.
  • This multiuse device is compatible with containers and sample tubes of various sizes and solution amounts.
9096
Customized 3D-Printed Bioresorbable Heart Valves
  • Resorbable, patient-specific heart valves offer great flexibility for treating a wider range of conditions and patients than traditionally manufactured heart valves. 
  • Customizable valves potentially decrease complications due to poor fit and the need for reinterventions.
  • Selecting materials for optimal mechanical properties, thermodynamic properties, chemical properties, and surface chemistry and morphology reduces mismatch between device and tissue, potentially improving performance and patient outcomes.
8893
Paper-Based Multi-Well Depletion Enzyme-Linked Immunosorbent Assay (ELISA) Enables Point-of-Care (POC) Testing
  • Paper-based lateral flow assay automatically performs multi-well ELISA testing for POC titer measurements.
  • Simplifies ELISA testing by eliminating the need for centralized laboratories staffed with trained personnel who perform multiple steps in a specific sequence to execute the assay workflow.
  • Transforms a variety of ELISA-based tests into single-use, disposable dipstick tests to be used at the point of care or at home.
9124
Streamlined Combination Analysis by FORECAST Accurately Predicts and Identifies Pending Malware Attacks
  • Automating the combined techniques of memory forensics and symbolic analysis accelerates how fast an enterprise or government becomes aware of the true extent of malware’s capabilities.
  • When countering cyberattacks, FORECAST provides improved accuracy (94%, overall) with its automated analysis, which is crucial to helping cybersecurity efforts to efficiently focus on high-impact solutions.
  • FORECAST has the flexibility to be a valuable incidence response tool, even when malware is fileless since it uses the software’s memory image to accurately predict the program’s capabilities.
8581
Electric Field Treatment Creates Safe, Effective Antimicrobial Surfaces
  • Creates safe, effective antimicrobial surfaces via bacteria inactivation without the use of chemicals
  • Targets cell membranes or capsid, is less likely to induce antimicrobial resistance, and should be effective for antibiotic-resistant bacteria
  • Requires very short electrical pulses to achieve effective bacteria inactivation, potentially leading to better antifouling performance
9130
Parametric Resonance Approach for Efficient, Versatile Acoustic Power Transfer for Implantable/Wearable Devices, Sensing, and Communications
  • New class of transducers utilizes parametric resonance to convert acoustic energy from an ultrasonic source to a sustained electrical signal. 
  • Technology powers implantable biomedical devices, small wearable sensors, and other wireless charging applications.
  • Simple yet robust generation of stable electromechanical frequency combs is also possible in both air and liquid environments using a capacitive micro-resonator array.
7635, 9075
Customizable Smart Charging Solution for Electric Vehicles in Residential Areas
  • This customizable smart charger uses algorithms and a hardware prototype to control electric vehicle charging and optimize benefits to consumers and power grid operators. 
  • Consumers can charge according to their preference (e.g., minimize cost, maximize carbon-free energy usage, minimize charging time, or minimize battery degradation).
  • The smart charger selects charging profiles that delay charging to avoid excessive loads on the power grid.
8980
Chemically Modified Reduced Graphene Oxides (rGOs) Improve Strength and Qualities of Polymer Composites
  • Chemically modifying rGO creates improved dispersibility and miscibility that can be used in polymer processes as a composite reinforcement or coating material.
  • Easily scalable solution chemistry and purification/filtration makes the process economically feasible, resulting in a commercially viable material for many applications.
  • Melt lamination results in a robust conductive coating that is more durable than comparable polymer-based coatings and enables many electronically active device designs.
8297
Artificial Neural Network (ANN) with Unique Input Design that Significantly Reduces Computational Costs of Complex Engineering Systems
  • Neural network’s novel input can utilize first-order schemes and local patches and allows for discontinuities to be reflected accurately and with greater resolution than existing products.
  • This adaptable ANN can be adopted by commercial and scientific research as a stand-alone solution or in conjunction with existing software. 
  • Lower costs for running complex and repetitive computations can be achieved by implementing this neural network with an input system that processes low-cost numerical solution patches arising from two or more converging solutions.
8963
Improved Electrically Driven Temperature Swing Adsorption (ETSA) System for Faster, More Productive Direct Air Capture of Carbon Dioxide
  • This electrically driven temperature swing adsorption (ETSA) system uses sorbent-coated carbon fibers that exhibit Joule heating and rapid temperature swings for improved CO2 direct air capture (DAC).
  • Over ten times faster temperature controls and six times faster CO2 desorption rate in ETSA than temperature swing adsorption (TSA) operation under the same DAC condition
  • The dual-layered structure composed of a Joule heating core and CO2 adsorbing coating layer result in a larger amount of CO2 chemisorption.
9063
Melting Microneedle Patches Extend Drug Delivery Applications, Simplify Manufacturing, and Reduce Costs
  • Melting microneedles enable dispersion of both poorly soluble and water-soluble drugs, which eliminates the need for solvents for improved stabilization and broader applications.
  • Melting microneedles shorten manufacturing and drying time, eliminate the need to maintain a cold chain for storage and transportation, and reduce the ultimate cost of the microneedle patch.
  • The safe suppository bases are inexpensive and enable control of the drug release timing.
8904
Quantitative, Performance-Driven Framework for Optimal Desalination Architectures and Energy Subsystems
  • Incorporate and simultaneously compare attributes of multiple types of both desalting systems and energy subsystems for optimal system architectures
  • Assess parameters that impact overall cost to discover complete architectures that would not have been discoverable using traditional methods.
  • Focus on renewable energy subsystems such as solar, wind, geothermal, hydroelectric, and others to create complete desalination architectures that are cleaner and more water efficient than their conventional counterparts. 
9055
Novel Nanocarriers Strengthen Therapeutic Delivery, Improves Efficacy
  • Greater therapeutic effectiveness is due to the synergistic work of multiple therapeutic agents (hydrophobic/hydrophilic charged) that can be delivered via this dual-loaded biomaterial.
  • The risk of immunotoxicity to a vaccine is reduced because an adjuvant, which can induce the body’s anti-inflammatory immune response, may be loaded and simultaneously delivered with the vaccine. 
  • The novel nanocarrier has broad market application since it can deliver vaccines, gene therapy, small molecule drugs, and even contrast agents.
8988
Automated Bioreactor Sampling System Can Eliminate Cross-Contamination of Samples
  • Automated bioreactor sampling system maintains sample integrity by changing the syringe between samples
  • In addition to savings related to reduced cross-contamination, automated sampling can further lower costs by reducing hands-on time and speeding sampling.
  • Flexible platform can be used with any type of collected sample.
8886