Available Technologies by Category
Targeted Single Cell Electroporation for Gene and Cell Therapy
  • The technology enables high efficiency delivery and high post-electroporation cell viability compared to current commercial electroporation systems.
  • The technology performs in-flow single cell measurements integrated with electroporation unlike current commercial electroporation systems which have no single cell measurement capabilities.
  • The technology enables automatic feedback control and real-time optimization of electroporation parameters at the single-cell level unlike current commercial electroporation systems which apply the same parameters to all cells in a batch at a bulk scale.
  • The technology enables selected or targeted electroporation and delivery to selected cells or cell types from a mixture of cells unlike current commercial electroporation systems which require upstream or downstream cell sorting steps.
9086
Tactical Gloves for Accurately Tracking Munitions Use
  • The gloves include an antenna that is woven into the palm of the glove, which is constructed of comfortable, flexible materials that can operate at a range of frequencies.
  • Morphological actuation in the gloves supports safe use.
  • To resolve operation ambiguities and improve safety, the gloves include a fingerprint scanner.
9014
TabAccess: A Wireless Controller for Tablet Accessibility
  • Enabling: Provides an alternative interface to touchscreen-based devices for people with limited fine motor control, potentially enabling them to interact with applications that could improve their quality of life or even create employment opportunities
  • Reconfigurable: Sensor modules can be interconnected as well as separated and mounted anywhere (e.g., on the human body or on a table, floor, wheelchair, etc.), enabling adaptation of the device based on the capability, range of access, and the individual’s range of motion.
  • Adjustable: Uses an adjustable Velcro strap so one size fits the majority of forearms
5946
Systems and Methods for SmallSat Propellant Positioning
  • The technology provides a way to reliably and efficiently control saturated, or boiling, propellants compared to existing technology.
  • The technology can easily be scaled up and applied to different liquids and architectures.
  • Significantly enhances the reliability and efficiency of current positioning methods.
9165
Systems and Methods for Flexible Sheath Locking with Integrated Shape Sensing
  • This technology aims to become a new steerable device to reduce the invasiveness of traditional methods for delivering drugs and diagnostic devices inside the body.
  • There are no known existing methods of delivering radiotherapy without the potential of adversely affecting healthy cells.
  • This device and method will enable drastic improvements in the quality of life of patients having to undergo radiotherapy treatment. 
9264
System for Bone Regeneration
  • Provides superior retention and release of osteoinductive protein
  • Reduces necessary dose of osteoinductive protein
  • Reduced cost of procedure
4660
Synthetically Generated, Realistic, and Controllable Human Bio-Signals from Participant-Free Data Collection
  • Synthetic data generation system replicates human body signals and uses a deep generative model to create synthetic SCG beats without human participants. 
  • Transformer-based generative model synthesizes SCG beats that are physiologically diverse and realistic. 
  • Clinically relevant feature inputs act as controls for aortic opening (AO) and aortic closing (AC) features of the generated SCG beat.
9081
Synthetic Nano-Antibodies for Immunotherapy
  • Cheaper and faster to manufacture- production only involves synthesis of ligands, nanoparticles, and nano-antibodies; it does not involve cell-lines or animal work
  • More effective- better accumulation and penetration is achieved due to the nanoparticle design
  • Better for patients- dosage to achieve therapeutic efficacy is reduced and can lower the price, duration, and frequency of treatment
7554
Synthetic Hydrogels for Human Organoid (HO) Generation and Transplantation
  • Synthetic hydrogel exhibits high cytocompatibility and minimal toxicity and inflammation in vivo for improved human organoid viability 
  • Injectable delivery vehicle supports localized HO engraftment in mucosal wounds to potentially enhance wound closure and repair
  • Modular design and delivery via endoscopic techniques enables the translational potential of this delivery platform for regenerative medicine and overcomes limitations associated with the use of commercially available matrices for hPSC-based organoid technologies
7536
Synthetic Hydrogel for Satellite Cell Delivery in Dystrophic Skeletal Muscle
  • Addresses the critical need for a viable treatment for deterioration of the diaphragm, which is a leading cause of respiratory failure and death in Duchenne Muscular Dystrophy patients
  • Engineered hydrogels comprised of synthetic polymers and peptides are designed to enable successful muscle satellite cell (MuSC) transplantation to the diaphragm or other dystrophic skeletal muscle tissue
  • Shown to support MuSC survival, proliferation, and differentiation, which can enable restoration of dystrophin – a protein absent in DMD and critical to strengthening and repairing muscle fibers
7841
Synthesis of Alkaloids

This technology can be used in the development of yeast-based syntheses of plant alkaloids, or any other biosynthetic pathway that uses 5-hydroxytryptohan or L-DOPA as precursors. It can be used for the synthesis of compound monoterpene indole alkaloids derived from strictosidine (e.g. quinine, camptothecin, ajmalicine, serpentine, vinblastine and vincristine) or benzylisoquinoline alkaloids derived from dopamine (e.g. berberine and morphine).

6817
Synthesis and Patterning of Polymer Nanowires
  • Reliable
  • High-throughput
  • Low-cost
4293
Syntactic Foam For Use As a Noise Suppressor
  • Reduces pressure pulses from “fluid-borne noise” which fatigue mechanical seals and cause system leaks
  • Reduces “structure-borne vibrations” that create operator discomfort and make it difficult to control tasks that require precision
  • Reduces “air-borne noise” that disrupts work-site communication and creates a hazardous work environment
6730
Sutures with Porous Sheaths for Drug Delivery
  • Accelerated wound healing and tissue regeneration through drug-eluting sutures
  • Increased drug loading and sustained drug delivery due to the interconnected porosity feature of the sutures
  • Release of cytokines, extracellular matrix proteins, anti-inflammatory, anti-microbial, and pain management drugs to injury site
7164
Sustained Lymphatic Drug Delivery System Potentially Improves Efficacy and Safety of Immunotherapy and Targeted Therapies
  • This sustained lymphatic drug delivery system guides therapeutics and imaging agents to the injection site, lymphatic vessels, and lymph nodes. 
  • Sustained lymphatic delivery enables lower dosing and fewer administrations to potentially improve therapeutic response while reducing adverse effects and costs.
  • The simplicity of a vaccine-like, sustained drug release injection allows use at less expensive community health centers.
8637
Sustainable Combination Technology Delivers a Long-Lasting Self-Powered Battery
  • Continuous: Regulates power harvested in the presence of constant mechanical motion to store excess energy while pushing a constant voltage to the external load
  • Eco-friendly: Reduces the need for consumers and technology developers to utilize supply-limited traditional batteries that are thrown away after a short use and could leak harmful chemicals into the environment
  • Sustainable: Eliminates the need to mine an additional power supply by harvesting energy from underutilized electrostatic induction found in naturally occurring mechanical motion
6418
Surface Nanomodification by Microwave Hydrothermal Treatments
  • Cost and Energy efficient- requires shorter times of surface modification with a lower concentration of solvents
  • Less hazardous- lower concentrations of solvents decrease the negative environmental impact
  • Versatile- though primarily related to biotechnology, this method can be applied in any industry requiring surface modification
5784
Surface Electrode Ion Trap for Cellular Analysis
  • Cells contained in charged droplets of solution and levitated above the surface electrode ion trapped by electromagnetic fields
  • Enables sorting of cells by optical, chemical, and/or physical properties
  • Merging of droplets is controlled allowing researchers to add chemicals and nutrients to cell environment one cell at a time
6970
Superomniphobic Paper
  • Cost effective
  • Higher oil repellency than currently available
  • Can be modified to repel other substance
6222
Superluminescent Light Projection (SLP) System Decreases Nanoscale Printing Costs by 10–50 Times
  • This superluminescent light projection (SLP) system decreases overall nanoscale printing costs by 10–50 times. 
  • A parallel writing mechanism supports higher throughput speeds: up to 100 times higher than existing metal printing methods and four times higher than existing polymer printing methods. 
  • SLP creates sharp-edged images with minimal speckling patterns, resulting in high-resolution images and structures on both polymer and metal-based films. 
9066