Available Technologies by Category
MINTED: Simultaneous Deformation and Temperature Imaging
  • Simultaneous recording of small-scale temperature and deformation fields at high spatial and time resolutions
  • Studies deformation, failure, and heating in a range of materials
  • Analyzes/monitors heating and failure of MEMS devices, microchips, and circuit board
Minimizing Power Failure from Weather Disruptions
  • Efficient – Allows power grid resilience for a community to be determined in the best possible manner by the electric utility while minimizing the impact of weather-related events
  • Analytical – Capable of analyzing and determining spots most or least resilient as well as time durations between failure and recovery
  • Customizable – Ability to tailor the model’s overall framework to include global and local parameters in the analysis and determination of performance issues
Miniaturized Modular-Array Fluorescence Microscopy
  • Powerful: Offers high fluorescence sensitivity, efficiency, and spatiotemporal resolution (~3 µm and up to 60 Hz)
  • Configurable: Offers compatibility with conventional cell culture assays and physiological imaging, providing accessibility to upright physiological imaging and integration with biochemical sensors under the cell platform
  • Efficient: Provides effective parallelization of multi-site data acquisition
Microscale High-Throughput Phenotypic Assay for Fibrosis
  • Powerful: Provides high-throughput image-based analysis of fibrotic processes as well as fibrinolysis
  • Convenient: Combines label-free readouts for fibrin degradation, collagen synthesis, and cell contraction to evaluate fibrotic tissue remodeling
  • Enabling: Opens new opportunities for understanding fibrosis pathogenesis and for evaluating anti-fibrotic therapeutics
Microrobots for Neurosurgery Applications
  • Minimally invasive: Significantly reduces invasiveness of procedures in comparison to current macroscale, neurosurgical robots 
  • Precise control: Uses 3D position data of the microrobots on the brain surface in a closed-loop system to adjust the magnetic field parameters (i.e., magnitude, frequency, phase, and direct current [DC] offset of each coil) as well as the forces the robots exert to the biopsy tissue
  • Facilitates movement: Employs microfabricated shapes that dictate the microrobot's movements, limits their contact with the brain surface to reduce adhesion, and may also provide a means for the robot to propel itself in fluid
Microneedle Coating
  • Alternative method for hypodermic needles
  • Coating uniformity
  • Spatial control on coating length
Microgeodes Enable Tunable Optical Response for Advanced Coatings/Paint
  • Microgeodes have a programmable structure of nanowires that allows their optical response to be engineered precisely over multiple spectral bands, from UV through mid-IR. 
  • Microgeodes combine the tunability and versatility of nanowires with the processability of microspheres to provide a photonic materials platform for a wide range of applications. 
  • Microgeode paints could reduce building surface temperatures by as much as 25°C, offering the potential for significant consumer savings while retaining aesthetically pleasing colors.
Microfluidic System Enables Scalable, High-Throughput Separation for High-Purity Human Induced Pluripotent Stem Cells (hiPSCs)
  • Simple, tunable high-throughput process separates hiPSCs quickly and efficiently according to the degree to which they adhere to a substrate inside the microfluidic device. 
  • Separation of intact cell colonies enables this simple system to avoid damaging and adversely affecting the pluripotency of the cells.
  • The approach is fast, does not rely on labeling technologies, supports greatly enriched cells, and results in a cell survival rate greater than 80%.
Microfluidic Platform for Phase Separation of Aqueous Solutions
  • Efficient workflow-  sample removal and analysis can be performed without manual oversight
  • Smaller sample size- less sample volume required alleviating dilution of low concentration solutions that is common in alternative sample preparation workflows
  • Faster process- thermoelectric cooling can induce separation in a matter of seconds with precision and tunability
Microfluidic Platform for High-Density Cell Delivery
  • Allows for hundreds of cells to be immobilized on a very small footprint- including non-adherent cells
  • Can analyze cell response at a single-cell resolution
  • Can simultaneously observe cell response and generate chemical cues- allows for observation of immediate cell response
Microfluidic Droplet for Drug Delivery and Therapeutic Applications
  • Viable, cellular micro-environments requiring precise control are achieved using hydrogel microspheres with diameter sizes ranging from 10-1000 micrometers
  • A protective, semi-permeable capsule encases the cells and biomolecules
  • Release rates of encapsulated biomolecules or drugs are controlled by adjusting the polymer parameters used to fabricate hydrogel microspheres
Microfluidic Device for Cell Aggregates
  • Control - Precise control over the cell culture environment
  • High content assays – Multiple types of imaging-based assays can be done on the same sample, both during live culture and at end-point
  • High throughput – Greater number of experiments
Microfluidic Device Enables Prediction of T-Cell Ability to Home and Engraft to Disease Tissues
  • Improve the homing capabilities of T cells to increase adoptive cell therapy treatment response and safety while decreasing off-target effects.
  • Enhance tumor-infiltrating capabilities with engineered microfluidic devices that identify optimal subsets of cells.
  • Optimize development pipelines by reducing the number of laborious in vivo studies, while also helping cell therapy companies ensure their products reach the desired tissue.
Microfluidic CODES with Innovative Machine-Learning Analysis
  • Scalable: Set-up allows for the integration of multiple microfluidic devices to increase throughput volume.
  • Versatile: Machine learning analysis can be applied to other microfluidic devices integrated with the same Coulter sensor network.
  • Pragmatic: This innovation improves the capabilities of lab-on-a-chip systems to provide an affordable solution for low-resource settings.
7107, 8032
Micro-scale Fuel Processor for Hydrogen Fuels
  • Scalability — processor can be configured for a variety of processes
  • Ease of operation — simple and robust
  • Compact — overall design can be only a few millimeters to a few centimeters in size
Methods to Impart Color and Patterns on Metal
  • Long Lasting: Does not wear off or fade
  • Stream-lined: Eliminates the need for paint touch-ups and repairs
  • Cost Effective: Prevents costly repair of material damage caused by paint
Methods of Recycling and Replacing Lithium Ion Batteries
  • Low cost – low energy use compared to other methods
  • Environmentally friendly – low emissions
  • High purity – accurate separation of high value metals from other components
7892, 7941
Methods for Sensing Wearouts of Electronic Circuits
  • Circuit details are taken into account in estimating lifetime
  • Wearout methods can be used to determine “timing closure” at 10 years lifetime
  • Methods serve as foundation for a new electronic design automation tool for “timing closure”
Methods for Generating Palladium-Rhodium Hetero-Nanostructures
  • Improved performance: Core-frame structure enhances shape stability and catalytic activity at high temperatures.
  • Cost effective: Less rhodium is used than with other crystal growth methods.
  • Simple: Crystals are formed in a scalable solution-based process.
Methods for Generating Functional Therapeutic Cells
  • Novel – No present technology exists
  • Versatile – Can be adapted to suit a variety of diseases, human and animal
  • Targeted – Antigen-binding qualities within the B cell allow for highly specific therapies