Technologies | Page 11 | Technology Licensing

Available Technologies by Category

Heat-Responsive Programmable T-Cells Specific: The remote programmable nature of these T-cells allows them to be selectively activated only in the necessary locations. Protective: This focused, genetically engineered immunotherapy is intended to protect patients from the additional harm of the off-target cell death and unnecessary systemic damage that is more common with oncological therapeutics. Non-invasive: With NIR light’s ability to penetrate into multiple layers of biological tissue and be absorbed by AuNRs, this technology removes the need for a light source in the body to trigger the T-cells.	7422
Heat Dissipation for Microelectronic Systems via Capillary Trap Effective: Dissipates large heat fluxes via 3D heat spreading and evaporative cooling that could approach kW/cm2 and beyond while keeping the surface temperature under 90oC Preventive: Mitigates coolant dry-out at the critical heat flux levels that result in a rapid and large temperature rise and thus cause device burn-out Efficient: Exploits high cooling capabilities associated with phase-change heat transfer through evaporation	6272
Heart Valve Docking System with Precision Positioning and Variable Sizing Versatile: Enables the THV to function in up to 80% of patients while reducing the current risks of complications, such as embolization Precise: Allows a THV to be delivered, positioned, and docked at the junction of the IVC and/or SVC and at the right atrium junction Secure in most any size junction: Compensates for most size differences between the landing site and the size of the THV itself to allow for secure anchoring without the need to create a larger THV	8408
Hardware Integrator for RDBMS and Machine Learning Accelerators Faster and more energy efficient execution of learning algorithms Ensure compatibility between hardware accelerators and data in RDBMS	7836
Handheld Breath Collection Device for Detecting Disease Biomarkers Improved diagnosis: Analyzes both the gas and liquid sampled from the patient’s breath for potentially more robust and multifaceted results Enhanced patient experience: Requires a shorter exhalation cycle to get a breath sample, making the test more comfortable for patients Small and portable: Optimizes and miniaturizes the collection process for easy point-of-care applications	8791
Hairbrush Inspired by Cat Tongue Grooming Mechanics Easy to clean: Easy removal of hair between bristles Adaptable: Can conform over any curved surface Effective: Claw-like shape of the spines enables a firm grip to any snag	7460
Guided Injection of Charged Cargo for Intracellular Delivery Novelty – use of an electrically-charged liquid beam of electrospray Improved control – control of action on the scale of single cell/single pores Diversity – arbitrary diverse set of cargo	8275
Graphene Transistors: Nanoscale Electronic Components Faster: Near-ballistic charge transport properties Cooler: Virtually no heat generation at high speeds Stronger: 100 times stronger than steel	5766
Grain Structure of Stainless Steel for Anti-Wetting Properties Utilizes intrinsic grain structures of stainless steel to modify surface wettability More efficient fluid transport and reduced energy consumption Does not require the deposition of additional coatings	7096
GPCR-Based Biosensors for Medium-Chain Fatty Acids Innovative – first medium-chain fatty acid biosensor Cost Saving – enables more rapid production Diverse applications – applications that require different dynamic and linear ranges	6767
Glucose Regulation Via Electrical Stimulation Of Nerves Needle-free blood glucose control. Potential to either eliminate or decrease use of blood glucose control medications. First demonstrated use of electrical stimulation to inhibit nerve activity to cause a decrease in measured blood glucose levels	6745
Germination Platform for Cost-Effective Plant Production Cost effective: Simply and inexpensively produces large numbers of high-quality plants from somatic embryogenesis Convenient: Permits easy handling and transport of germinated propagule Practical: Produces high-quality straight roots	6888
Generative Causal Explanations for Black-Box Classifiers Increased trust: Has the potential to improve the transparency and fairness of machine learning systems and increase the level of trust users place in their decisions Flexible explanation vocabulary: Provides a rich and flexible vocabulary for explanation that is more expressive than feature selection or saliency map–based methods Deeper insights: Offers visualizations that can be much more descriptive than saliency maps, particularly in vision applications, leading to better user understanding	8507
Generating Power via High-Efficiency Electrochemical Converter Lower cost: The working fluid and storage materials are inexpensive. Multifunctional: Multiple functions (e.g., solar conversion, thermal storage, electrochemical storage) can be integrated in a single system. High efficiency: This device’s heat-to-electricity conversion has the potential to be twice what has been achieved previously.	7065
Gaussian Switch Sampling (GauSS) for Training Deep Neural Networks Better analyses: It provides a method to analyze models and their interaction with data. Improved accuracy: By matching or outperforming existing technologies in terms of test accuracy on in-distribution as well as out-of-distribution applications, GauSS is more selective and finds samples that help the network learn as well as remember things previously learned. Versatile: The strategy is based exclusively on learning dynamics and, therefore, can be generalized across networks, data, and training methods.	8757
Fully Passive, Long-Range Radio-Frequency Identification (RFID) via 5G Large coverage: Provides a unique combination of large angular coverage and turn-on sensitivity in both planar and bent configurations Long range: Demonstrates the potential for RFIDs with practical reading ranges over 1.8 km Scalable: Scales in size to a precise degree, enabling selection of the optimal tradeoff between size and harvested power/reading range	8141, 8439
Fully Integrated, Piezoelectric Standalone MEMS Frequency Combs Compact: Provides a fully integrated package with a smaller footprint (30 μm x 30 μm) compared with CMOS-MEMS configurations Robust: Offers higher sensitivity and enhanced detection limit compared with the previous state of the art Low noise: Lowers shot noise levels associated with electronics and MEMS circuitry by eliminating the need for circuitry like electronic amplifiers	7875
Fuel-Optimal Flight in Uncertain Wind Accurate: Process uncertainty model provides more accurate results than current models Efficient: Optimization model provides fuel-optimal air speed over flight path Novel: First method to leverage knowledge of wind forecast uncertainty in a random process framework	5878
Fuel Cell Membranes That Operate at High Temperature High conductivity at high temperature and low humidity Mechanically stable — PEMs do not tear or deform under normal operating conditions Reduced acid leaching — unique acid doping between layers reduces leaching, which prolongs the life of the fuel cell	4346
Frequency-Output Gyroscope Low-cost Constant resonant frequency of the drive mode Better sensitivity – minimal detectable frequency is only limited by short-term stability and counting period length	4682
Fourier Light-Field Microscope (FLFM) for Fast, Volumetric, and High-Resolution Imaging of Entire Organoids Cost-efficient and scalable: Is fully adaptable to epifluorescence protocols resulting in a system that is both cost-efficient and highly scalable Fast: Captures fast cellular and tissue dynamic processes in a simultaneous, volumetric manner (e.g., collective cellular responses at sub-second time scales across whole samples) Validated: Responses to extracellular physical cues such as osmotic and mechanical stresses have been recorded using human induced pluripotent stem cell-derived colon organoids (hCOs).	8844
Four-Dimensional Electron Density Mapping of the Ionosphere Innovative: Produces the first four-dimensional image of electron density in the lower ionosphere Far-reaching: Leverages technology that can be used efficiently on a global scale Pragmatic: Yields a highly useful four-dimensional map to be used in military and commercial applications that rely on high-frequency communications	8349
Foot GO: The Foot Granular Orthosis Customizable: Can easily adjust fit and stiffness Simpler: Has potential to simplify the foot orthosis manufacturing process Re-conformable: Custom fit and stiffness can be readjusted multiple times for changing needs over time	7338
Foldable Box Kites for Generating Electricity Robust – dynamic stability enables much easier control of the comprised of box kites Increased generation –the kite can access and capture much stronger and steadier winds Simple – components are easier to manufacture and install and maintain	8185
Fog-Free GTE Ventilated Face Mask Unique- fog-free patient eye-contact Non-invasive- reduced stress in extended medical staff contact with patients Simple- economical and durable	7138
Fluorescent Nanoprobes for Live-Cell RNA Imaging Sensitive — can image single molecules with multiple emission wavelengths Fast — probe is multivalent and bind to RNA in less than 10 minutes Low cost — the alternative dual-label probes are more expensive	4513
Fluorescence Microscopy with an Ideal sCMOS Camera Fast – produces fully quantitative sCMOS image restoration up to 100 times faster than the current state-of-the-art Accurate – produces fully quantitative sCMOS image restoration up to two orders of magnitude more accurate than the current state-of-the-art Improved features – allows a broad range of imaging techniques without compromising data reliability	8098
Fluid Management System for Hemofiltration Compact- size addresses concern of restricted bed-side space Age-friendly- potential use in any age group, from newborns to adults	4209
Fluid Interface–Supported Printing Process for Stereolithography 3D Printing Reduced costs: Lowers costs by using less resin and requiring less user effort for support removal and post-processing Faster printing: Produces parts more quickly and easily Enhanced creation of complex geometries: Enhances the ability to create more detailed and complex structures using SLA 3D printing	8774
Flight Control System for Miniature Aerial Robots Lightweight: Features a core electronics board that weighs less than half a gram Flexible: Contains a core electronics board that can be conveniently reprogrammed for expanded functionality Compact: Offers a small form factor with an area of about 2 square centimeters	8591
Flexible Power Generation with Negative Carbon Emissions Energy security: This system enables the continued use of low-cost domestic fuel (i.e., natural gas) for electricity generation and increases the reliability of U.S. electricity production. Environmental protection: Flexible carbon capture and storage (CCS) systems can achieve high CO2 capture rates from flue gas. For example, with this system a power generator could shift the times it exports electricity to the grid, allowing the power generator and CCS plant to operate under steady-state conditions and with reduced emissions. Reduced costs: The cost of a net-zero carbon electricity system is lowered by providing dispatchable power to a high-VRE grid.	8834
Flexible Electrical Interconnects with Concave/Convex Platform Co-fabrication of very complex interconnect structures for developing and testing different system topologies Improved system performance while increasing packaging density with little or no impact on the fabrication process steps used Complex shapes easily fabricated without compromising the mechanical strength or the electrical performance	6957
FlashStream: A Multi-Tiered Storage Architecture Optimized for Video Streaming Flashstream designed specifically for video streaming; whereas alternative storage systems are general purpose resulting in degraded video Prototype Flashstream, which optimizes caching, performed 2X better than its nearest competitor, Oracle Solaris ZFS. Directly accesses the SSD and RAM to achieve Quality-of-Service (QoS)-sensitive caching to better prioritize changes in video workloads	6264
Fine-Pitch Chip-to-Substrate Interconnect Assemblies for Advanced Electronics Applications Secure: Forms a mechanical locking structure via the bump and substrate deformation Strong: Relies on compressive stresses developed during the adhesive curing process to create the connection between chip bumps and substrate pads Economical: Costs significantly less than interconnect assemblies made with gold bumps	4878
Field Measurement of Gas Fluxes Using a Non-Gradient Method Costs: lower equipment and operation cost without compromising measurement accuracy Efficiency: efficient modeling gas fluxes at diurnal and seasonal scales Applicability: natural and pollutant gases over all types of land surfaces.	7990
Fibrin "Knob" Therapeutics Simple method Robust production Innate therapeutic potential	4021
Fast Microscale Actuators for Probe Microscopy Enables fast and parallel actuation with integrated electrostatic actuators and built-in optical displacement sensors Accurate force measurement with nanometer resolution in parallel single-molecule mechanics experiments Novel FIRAT structures for high speed AFM imaging in liquid environments	3916
Fast Evaporating Polymers and Copolymers Cross-linking Incorporation of small molecules that are capable of amplification Residue reduction Waste elimination	7472, 7645
Facilitating Ultrasound Penetration of the Skull for Diagnosis and Treatment Portable: Designed to enable imaging of the brain via small, mobile ultrasound devices, which may offer greater convenience compared with MRI and CT machines Affordable: May be a lower cost modality compared with leading techniques, such as MRI, CT, or positron emission tomography (PET) Robust: Demonstrates energy transmission through the skull on par with that of an aqueous medium in preliminary testing	8340
Facile Synthesis of Ultrathin Silver Nanowires Produces Ag nanowires less than 20 nm in diameter, with high aspect ratios (over 1000), and in high yield (>85%) One pot, quick (< 35 min) synthetic process that is performed under ambient pressure Great mechanical flexibility and can be bent at acute angles without breaking	6791

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