Technologies | Office of Technology Licensing

Available Technologies by Category
Ribonucleotide-Capture Method	Enables the mapping of precise-genome wide positions of rNMPs incorporated in genomic DNA Results in sensitive and specific identification and mapping of rNMPs Could be used for further understanding of the biological implication and consequences of rNMP incorporation in DNA	6522
A Method for Exhaustive CRISPR Off-Target Analysis	Provides exhaustive genomic searches for off-target sites due to mismatches, deletions, and insertions Provides primers for experimental validation of predicted off-target sites Facilitates experimental testing using assays or deep sequencing of potential off-target sites given in the output	6478
Advanced Techniques in Floating-Gate Transistor Programming	Precise Smaller switch count Fewer parasitic	3458
Microfluidic Device for Cell Aggregates	Control - Precise control over the cell culture environment High content assays – Multiple types of imaging-based assays can be done on the same sample, both during live culture and at end-point High throughput – Greater number of experiments	7720
Electrical Contact Geometry for Switchgear Applications	Faster operation Enabling of fault current limitation Reduction in risk of damaging electrical equipment	7703
Embedded Wireless Temperature Sensor for Orthopedic Implants	Utilizes temperature as indication of deep tissue infection Deep tissue measurement vs. only reaching skin surface Non-invasive monitoring	7682
Thermoelectric Interconnects	Efficient – Increased power density for powering sensors, wearable devices, and personal power generators Cheaper – Fabrication utilizes classic, lower cost roll-to-roll processing techniques Market Specific – Better suited to these current markets than traditional inorganic TE materials	7677
Blind Selected Mapping for OFDM	Less distortions – achieves a better peak-to-average power ratio Cheaper – lower cost solution	3425
Cancer Diagnosis Using Nanotechnology	Can be used with a simple microscope More sensitive and cost-effective Non-toxic	3424
Microfluidic Droplet for Drug Delivery and Therapeutic Applications	Viable, cellular micro-environments requiring precise control are achieved using hydrogel microspheres with diameter sizes ranging from 10-1000 micrometers A protective, semi-permeable capsule encases the cells and biomolecules Release rates of encapsulated biomolecules or drugs are controlled by adjusting the polymer parameters used to fabricate hydrogel microspheres	6467
Disease Progression Modeling	Accurate - Provides continuous time modeling, which is more appropriate for medical data due to patients being monitored at irregular intervals Multipurpose - Could be used for disease staging, characteristic progression pattern discovery, prediction of the future state of disease, fast local progression detection, and to enable understanding of disease progression	6466
New Imaging Tool to Compare Healthy and Diseased Cells	Discrimination between healthy & diseased cell biology Personalized medicine – specific treatment for an individual Diagnosis of a disease prior to symptoms	6458
Assistive Stairs Utilizing Energy-Recycling Technology	ERAS are the only energy-recycling device tailored for assistance during stair movement. The modular design of ERAS allow for quick and easy installation (and removal, if necessary) on top of an existing staircase without expensive remodeling. The low-cost and low-power design allow ERAS to be more affordable and practical to people with limited financial resources.	7596
Cable-Driven Four-Bar Link Leg Mechanism	Reduces the weight and improves performance of the mechanism by placing all actuators inside the body Structurally efficient – significant portion of loads are carried by the cable which is an efficient structure Actuator loads are significantly reduced through mechanism linking, increasing the longevity of the mechanism	7592
Rubber Encapsulated Pressure Sensor for Contact Sensing	Controllable design for tunable force response Force and pressure sensor characteristics can be easily tailored Protected pressure sensor from high forces and pressures	7591
Synthetic Nano-Antibodies for Immunotherapy	Cheaper and faster to manufacture- production only involves synthesis of ligands, nanoparticles, and nano-antibodies; it does not involve cell-lines or animal work More effective- better accumulation and penetration is achieved due to the nanoparticle design Better for patients- dosage to achieve therapeutic efficacy is reduced and can lower the price, duration, and frequency of treatment	7554
Thermal Resistance Solution for Power Electronics	Customized substrates: Use of low cost and readily available bonding materials enable easy, customized manufacturing of substrates for packaging power modules. Efficient heat transfer: Durable and high thermal conductivity bond material >130 W/mK. Low thermal resistance substrate/cold plate system. Longer life cycle: Increases mechanical integrity, reduced CTE mismatch.	7549
PUPS: Pressure Ulcer Prevention System	Enhanced quality of care: Patients are less likely to develop a hospital-acquired infection Lower cost: Minimizes costs from “never events” such as pressure ulcers	7541
Biopolymer Fabricated Materials for Biomaterials	Novelty – first technology that enables the formation of biopolymer brushes at interfaces of any thickness Incredibly biocompatible – hyaluronan has many salient features such as being non-fouling, non-immunogenic, and viscoelastic that make it a common polymer used in biomedical applications Potential for regenerative technology – further applied in regenerative interface technology research	7535
Multiple Degree-of-Freedom Micro-Scale Guidewire	Lays the foundation for developing the world’s smallest bidirectional motion capable, multi-DOF, mechanically actuated guidewire Achieves individual control of each degree-of-freedom Enables greater range of motion and steer ability at anywhere along the length of the guidewire compared to traditional active guidewires	7532