Melting Microneedle Patches Extend Drug Delivery Applications, Simplify Manufacturing, and Reduce Costs Dissolving microneedle drug delivery applications are limited by drug/biomolecule solubility/instability |
8904 |
Novel Nanocarriers Strengthen Therapeutic Delivery, Improves Efficacy Overcoming limited durability and variant response in vaccine development and delivery |
8988 |
Automated Bioreactor Sampling System Can Eliminate Cross-Contamination of SamplesMany bioreactor sampling systems have cross-contamination |
8886 |
Efficiently Generating Complex Hydrogel Structures for Tissue/Organ-on-a-Chip ModelsFaster approach cuts development time to minutes while using simple instruments |
8838, 8839 |
patcherBotPHARMA Automated Intracellular Pharmacological Electrophysiology RobotProvides faster throughput and less hands-on time for complex pharmacological patch-clamp experiments |
8717 |
Simulated Synovial Fluid Offers Potential for Effective Treatment of Knee OsteoarthritisKnee Osteoarthritis Difficult to Treat Despite High Prevalence |
8956 |
“Smart” Feedback-Controlled Bioreactor Platform Enables Consistent High-Yield and High-Quality MSC ProductsLarge-scale reproduction of high-quality hCT-MSC clinical cultures needed |
8887 |
Reducing Intraocular Pressure in Glaucoma Patients Without Drugs or Surgery via a Simple Hydrogel InjectionDrug-free and surgery-free management of intraocular pressure (IOP) may lower risks and increase patient adherence |
8467 |
Synthetic Hydrogel for Satellite Cell Delivery in Dystrophic Skeletal Muscle Current clinical interventions do not regenerate muscle tissue due to aging, trauma, and dystrophic disease |
7841 |
Synthetic Hydrogels for Human Organoid (HO) Generation and TransplantationCurrent HOs rely on tumor-derived extracellular matrices that limit their use in regenerative and translational medicine |
7536 |
Hybrid Molecular Catalysts: A New Blueprint for Catalyst Design, Preparation, and Testing Homogeneous molecular catalysts cannot be easily scaled up due to complex product separation and catalyst recovery |
8537 |
Advanced Manufacturing of Biodegradable Shape Memory Polymers Increases In Vivo SuccessGreater biocompatibility of polymers needed for biomedical implantations |
8658 |
Hydrogels for Controlled Delivery of Lysostaphin to Treat Staphylococcus aureus InfectionsOrthopedic hardware infections lack effective treatment options |
7729 |
Scalable Manufacturing Approach of Graded Polymer Thin Film Has Potential for Widespread UseExisting Techniques for Fabricating Patterned Thin Films Fall Short |
8994 |
New Methods for Skin Tissue Engineering: Textile-Based Sandwich Scaffold and CNT-based Electrospun Polymer Composite YarnsBiocompatible, conductive materials with potential to mimic properties of human tissues |
8751, 8752 |
A Biological Computing Framework for Living SystemsProviding a foundation for programmable medicine |
8009 |
Smart Porous Hydrogels to Increase Cold Supply Chain Efficacy of Biologics and PharmaceuticalsDesigned to streamline storage and handling of biologics and pharmaceuticals, decreasing costs while increasing accessibility |
8685 |
A Chip-Scale Linear Ion Trap to Enable Portable Mass SpectrometersLowers size and weight while providing sub-unit resolution and high detection efficiency |
8137 |
Increasing Medium-Chain Fatty Acid (MCFA) Yield in Bacterial Host with Engineered EnzymeThree-fold improvement in MCFA production for enhanced biopolymer manufacturing |
7595 |
Scalable, Low-Cost, Inversion-Free Method of Enabling Automated Underside Cell Seeding For preparation of high-throughput co-culture tissue barrier models for drug discovery |
8677 |
Advancing Mass Spectrometry with Novel InterfaceUnique device improves size-selective collection and desolvation of charged droplets to enhance the sensitivity of mass spectrometry |
4182 |
2D Array DeviceAn open-surface 2D array device for high-throughput screening and selection of biosystems |
8253 |
Disposable Impedance Biosensor for Cell Manufacturing The developed biosensor for cell manufacturing yields a more accurate product, by wireless monitoring and control within the flow of the manufacturing system itself. |
8270 |
A Technique for Integrating Photographs for Medical Imaging ExaminationsMethods for generating an integrated image series that includes a patient image and medical image to avoid medical errors for patients |
6402 |
Microfluidic Platform for Phase Separation of Aqueous SolutionsA microfluidic system capable of accomplishing refrigeration induced phase separation of aqueous-acetonitrile solutions. |
8247 |
Method for Treatment of PathologiesA antiviral method that uses mRNA acting as a targeted RNA cleaving enzyme from various bacterial species |
7878 |
Organ Transplant Decision AidAn interactive decision support tool that estimates survival probability for potential organ transplant recipients |
8001 |
Pterin-Based Hydroxylation of Aromatic MonomersA method using a natural enzyme to modify lignin monomers |
6943 |
GPCR-Based Biosensors for Medium-Chain Fatty AcidsBiosensor to increase production of microbes for biofuel production |
6767 |
Method for Making Thermally Conductive MaterialsA method for the production of nanostructured surfaces and bulk composite materials that exhibit tunable surface morphology |
6725 |
A Method for Exhaustive CRISPR Off-Target Analysis A method for identifying off-target sites for research and the study of human diseases |
6478 |
Surface Nanomodification by Microwave Hydrothermal TreatmentsCost and energy efficient method for surface nanomodification for biotechnological applications |
5784 |
Polymer Wrapping of Single Wall Carbon NanotubesA method for helically wrapping carbon nanotubes with polymer to increase processing strength while preserving desirable characteristics of nanotubes |
7213 |