Medical Devices | Technology Licensing

Available Technologies by Category

Paper-Based Multi-Well Depletion Enzyme-Linked Immunosorbent Assay (ELISA) Enables Point-of-Care (POC) Testing Paper-based lateral flow assay automatically performs multi-well ELISA testing for POC titer measurements. Simplifies ELISA testing by eliminating the need for centralized laboratories staffed with trained personnel who perform multiple steps in a specific sequence to execute the assay workflow. Transforms a variety of ELISA-based tests into single-use, disposable dipstick tests to be used at the point of care or at home.	9124
Electric Field Treatment Creates Safe, Effective Antimicrobial Surfaces Creates safe, effective antimicrobial surfaces via bacteria inactivation without the use of chemicals Targets cell membranes or capsid, is less likely to induce antimicrobial resistance, and should be effective for antibiotic-resistant bacteria Requires very short electrical pulses to achieve effective bacteria inactivation, potentially leading to better antifouling performance	9130
Customized 3D-Printed Bioresorbable Heart Valves Resorbable, patient-specific heart valves offer great flexibility for treating a wider range of conditions and patients than traditionally manufactured heart valves. Customizable valves potentially decrease complications due to poor fit and the need for reinterventions. Selecting materials for optimal mechanical properties, thermodynamic properties, chemical properties, and surface chemistry and morphology reduces mismatch between device and tissue, potentially improving performance and patient outcomes.	8893
Parametric Resonance Approach for Efficient, Versatile Acoustic Power Transfer for Implantable/Wearable Devices, Sensing, and Communications New class of transducers utilizes parametric resonance to convert acoustic energy from an ultrasonic source to a sustained electrical signal. Technology powers implantable biomedical devices, small wearable sensors, and other wireless charging applications. Simple yet robust generation of stable electromechanical frequency combs is also possible in both air and liquid environments using a capacitive micro-resonator array.	7635, 9075
Wearable Ocular Electronics with Virtual Reality Solution for Effective Home-Based Vision Therapy The first fully portable and wireless ocular electronic system in a VR environment provides an effective, home-based visual therapy program. The integrated wearable system has a data classification algorithm to provide high-fidelity, real-time detection of eye vergence to treat eye disorders. Running a VR system on a smartphone can create “virtual therapies” that can be used anywhere anytime.	7916
Reducing Intraocular Pressure in Glaucoma Patients Without Drugs or Surgery via a Simple Hydrogel Injection Hydrogel injections alleviate elevated intraocular pressure (IOP) with fast results and extended impact. Surgery-free approach eliminates the risk of tissue damage caused by a surgical incision or laser application. Simplified and effective treatment process from standard daily drug intake to a brief office visit only once every 4-6 months.	8467
DetectIV Offers Noninvasive Early IV Infiltration and Extravasation Detection DetectIV provides a continuous, noninvasive, and wireless IV infiltration and extravasation detection system. The sensor does not cover the IV site and works well with all skin types—significant improvements over existing detection devices. The device detects infiltrations on average 2 hours ahead of nursing standard of care making it an effective early detection system that prevents extended hospital stays.	7207
Biodegradable Shape Memory Polymer for 3D-Printed Tissue and Biomedical Devices New synthesis reaction produces novel biomaterials for soft tissue treatment combines shape memory and biodegradability with custom 3D printing for patient-specific, minimally invasive solutions Customizable to patient needs by varying the formulation and molecular architecture to alter the mechanical properties Improves safety and efficacy by providing a much-needed middle range to existing “too hard/too soft” tissue repair options, while also being biodegradable and bioresorbable	8655
Synthetic Hydrogel for Satellite Cell Delivery in Dystrophic Skeletal Muscle Addresses the critical need for a viable treatment for deterioration of the diaphragm, which is a leading cause of respiratory failure and death in Duchenne Muscular Dystrophy patients Engineered hydrogels comprised of synthetic polymers and peptides are designed to enable successful muscle satellite cell (MuSC) transplantation to the diaphragm or other dystrophic skeletal muscle tissue Shown to support MuSC survival, proliferation, and differentiation, which can enable restoration of dystrophin – a protein absent in DMD and critical to strengthening and repairing muscle fibers	7841
Microrobots for Neurosurgery Applications Minimally invasive: Significantly reduces invasiveness of procedures in comparison to current macroscale, neurosurgical robots Precise control: Uses 3D position data of the microrobots on the brain surface in a closed-loop system to adjust the magnetic field parameters (i.e., magnitude, frequency, phase, and direct current [DC] offset of each coil) as well as the forces the robots exert to the biopsy tissue Facilitates movement: Employs microfabricated shapes that dictate the microrobot's movements, limits their contact with the brain surface to reduce adhesion, and may also provide a means for the robot to propel itself in fluid	8749
Eco-Method Mordant that Improves Natural Dye Adhesion to Synthetic Fabrics Eco-friendly: An improved industrial dyeing process because it reduces excessive heat and water contamination during manufacturing. Wide applicability: Demonstrated to be successful with other materials beyond polyester, including Kevlar and polyacrylonitrile (PAN). Improved quality: Improving commercial dye methods without losing the desired properties of polyester such as flexibility is beneficial to industries like medical supply.	9048
Advanced Manufacturing of Biodegradable Shape Memory Polymers Increases In Vivo Success Faster healing: Improvements catalyze the regeneration of tissue for a faster recovery Increased efficacy: Decreases the likelihood of rejection because the polymers are manufactured in such a way to increase tissue ingrowth and cell attachment Reduced healthcare resource utilization: When initial implantation is successful, it reduces the need for secondary procedures or advanced clinical care for infection	8658
Hydrogels for Controlled Delivery of Lysostaphin to Treat Staphylococcus aureus Infections Injectable (or surgically applied) hydrogel formulation conforms and adheres to the fracture and surrounding tissue, ensuring efficient, local delivery of lysostaphin Localized treatments enable higher relative doses to be given at the site of infection, and enhanced stability from the hydrogel carrier may reduce the number of overall doses needed Tunable nature of the material provides control over the amount and time over which lysostaphin is delivered	7729
Smart, Wireless, Bioelectronic Pacifier for Real-Time Continuous Salivary Electrolyte Monitoring in Infants Smart pacifier offers wireless, real-time, continuous detection of sodium and potassium levels in infants. This totally non-invasive monitoring pacifier eliminates the need for blood draws, which can only be done three times each day, and is designed to provide non-invasive neonatal health monitoring. Microfluidic channels are designed to efficiently pump optimum quantities and concentration of viscous saliva to the sensor area for quick measurement and to eliminate the need to induce salivary stimulation.	8942
Quantitative, Multiplexed Electronic Detection of COVID-19 Biomarkers Direct electronic detection: This innovation provides direct detection of biomarkers as a simple electronic readout without the use of any intermediate optics. Multiplexed: The device can simultaneously detect multiple biomarkers (e.g., a four-plex chip to detect IgG and IgM antibodies against spike or nucleocapsid antigens). Portable: A handheld, cellphone-interfaced reader is designed to enable detection and monitoring of diseases in remote areas for sensitive yet inexpensive point-of-care use.	8814
Recirculation System for Aerosol Collectors Maximizes Particle Concentration for Improved Pathogen Detection Enhanced detection: Continuously recirculated collection buffer increases the concentration of targeted particles collected and improves detection of pathogens Increased sampled air volume: Recirculating the buffer enables running the system for longer periods of time and with larger volumes of air to improve pathogen detection in entire buildings Increased control: Users have active control of the volume of fluid introduced during collection via the system’s recharge pump	8903
3D Light-Field Endoscopy for High-Precision Microsurgery Enhanced control and safety: Real time visual navigation enhances guidance and intervention in complex microenvironments, maintaining high spatial resolution while providing quantitative depth information Comfortable: System does not require 3D glasses that can cause physician dizziness or headaches after long periods of use Streamlined: Technique eliminates the need for other imaging procedures such as micro-CT or MRI to quantify the 3D morphology of tissue	8848
Cell-free Biosensors to Detect Creatinine, Creatine, and Sarcosine Portable: This technology demonstrates the potential to develop point-of-care screening and monitoring, which is essential to expanding access to care worldwide, including to low- and middle-income countries. Inexpensive: CFE-based biosensors can cost as little as a few cents per test and could provide a low-cost alternative to current renal function monitoring and diagnosis, which currently involves laboratory visits, trained phlebotomists, skilled technicians, and expensive, specialized equipment. Cell-free: The use of a cell-free expression system could enable easier-to-read quantitative output that is less susceptible to matrix effects.	8776
New Methods for Skin Tissue Engineering: Textile-Based Sandwich Scaffold and CNT-based Electrospun Polymer Composite Yarns Biocompatible: Exhibits good biocompatibility of the yarns fabricated using a wet electrospinning technique (results shown within a limited range of CNT concentration in the bath) Purposeful: Mimics the strain-stiffening behavior of human tissue, unlike other scaffolds that exhibit strain-softening of their synthetic materials Demonstrated: Exhibits the ability to guide cell anisotropic arrangement as well as support cell proliferation and infiltration in in vitro biological tests	8751, 8752
Wearable Device for Evaluating Post-Injury Ankle Health During Ambulation Better decisions: Helps clinicians more easily determine the best course for ankle rehabilitation and improves compliance with physical therapy Faster recovery: Enables improved rehabilitation guidance based on collected telehealth data that may speed the time to recovery Fewer re-injuries: Supports clinicians in making better decisions regarding appropriate activity levels and readiness to return to activities to avoid re-injury	8513
Transcatheter Heart Valve with Multi-Arm Mechanism Reduced flow stasis: This mechanism displaces the native valve leaflets away from the THV stent frame, essentially removing its “cover” and allowing blood to move freely through the open stent cells. This can help to significantly reduce flow stasis in the neo-sinus region, thereby reducing thrombus initiation/progression. Prevention of coronary artery obstruction: Coronary artery obstruction following TAVR is a rare but often fatal complication. In rare cases in patients with unusually large native leaflets or small aortic roots, the large leaflets block the flow of blood to the coronary arteries as the new valve’s scaffolding opens. Georgia Tech’s design displaces the native valve leaflets away from the THV stent frame, which can help to reduce this risk. Optimized THV deployment: The innovation offers dual feedback to aid clinicians in determining optimal THV deployment height—a key factor in optimizing patient outcomes. As the device’s “arms” extend against the native vessel wall, they create both tactile feedback during THV positioning as well as visual feedback via fluoroscopy. In addition to deployment height, the multi-arm design supports axial alignment of the THV with respect to the native vessel wall—a factor shown to impact valve performance.	8140
Low-Power Real-Time Ionizing Radiation Detector Sensitive: Detects the charge generated from the interactions of ionizing radiation within matter with a high level of precision and discerns X-ray pulses of varying dose Scalable: Covers a significantly larger detection area than other methods, ranging from 60,000 square micrometers to one square millimeter Responsive: Responds within microseconds and proportionately with the overall radiation dose when exposed to X-rays of varying tube voltage (energy) and tube current (number of particles)	8780
Gaussian Switch Sampling (GauSS) for Training Deep Neural Networks Better analyses: It provides a method to analyze models and their interaction with data. Improved accuracy: By matching or outperforming existing technologies in terms of test accuracy on in-distribution as well as out-of-distribution applications, GauSS is more selective and finds samples that help the network learn as well as remember things previously learned. Versatile: The strategy is based exclusively on learning dynamics and, therefore, can be generalized across networks, data, and training methods.	8757
Steerable and Flexible Robotic Endoscopic Tool with Instrument-Changing System Flexible: Offers multiple tendon-driven degrees of freedom and is designed to enable the surgeon to avoid obstacles within the workspace Simplifies instrument changes: Includes three instrument stations with a motorized shaft to allow insertion into or retraction from the working channel(s) without leaving the surgical field Reduces procedure time: Demonstrates potential to improve procedure efficiency and patient safety by reducing procedure time	8118
Wearable Health Monitoring Device Improves Data Quality and Accuracy High performance: Captures real-time, real-world data of multiple physiological signals with a significant reduction in MA interference Chest-mounted: Provides more accurate ECG, heart rate, respiratory rate, and activity detection than existing wrist-worn commercial monitors Comfortable: Adheres securely and discretely to the skin using a breathable soft membrane for continuous conformal contact, eliminating excessive sweating and skin irritation	8691
Robotically Steerable Guidewire for Improved Vascular Intervention Robotic: Provides operational improvement of guidewire navigation to facilitate catheter placement by employing robotics, while most other commercially available guidewires lack active steering capability Versatile: Controls the guidewire bending angle and also adjusts the bending length of the joint, increasing the capabilities of the guidewire and accommodating varied vasculature geometries Flexible: Can be extended to multiple bending sections and degrees of freedom, in stark contrast to passive guidewires that offer clinicians very limited degrees of freedom	8451
Handheld Breath Collection Device for Detecting Disease Biomarkers Improved diagnosis: Analyzes both the gas and liquid sampled from the patient’s breath for potentially more robust and multifaceted results Enhanced patient experience: Requires a shorter exhalation cycle to get a breath sample, making the test more comfortable for patients Small and portable: Optimizes and miniaturizes the collection process for easy point-of-care applications	8791
Heart Valve Docking System with Precision Positioning and Variable Sizing Versatile: Enables the THV to function in up to 80% of patients while reducing the current risks of complications, such as embolization Precise: Allows a THV to be delivered, positioned, and docked at the junction of the IVC and/or SVC and at the right atrium junction Secure in most any size junction: Compensates for most size differences between the landing site and the size of the THV itself to allow for secure anchoring without the need to create a larger THV	8408
Adaptive Broadband Impedance Matching in Ultrasound Front-End Electronics High performance: Improves power transfer and acoustic reflectivity Flexible: Enables multimodal and tunable operation of CMUTs Efficient: Provides optimal matching for co-design of CMUT electronics	8342
Drive Belt with Surface Texture to Minimize Vibrations Effective: Demonstrated significant reduction in vibration compared with flat, untextured belt surfaces in preliminary testing Simple: Provides a straightforward and easy-to-implement solution to a widespread problem Economical: Offers a far less expensive means of maintaining the operation of machinery compared with replacing worn belts or employing complex tension systems	8307
Novel, Non-Invasive Stimulation to Control Brain Inflammation and Boost Resilience to Stress Reaches deep brain regions: Drives rhythmic neural activity in deep brain regions that are unreachable by most non-invasive stimulation technology Non-invasive: Uses only lights and sound with precise timing and control Fast response: Effects are seen in 5 to 30 minutes rather than hours	7773, 7832, 8745
High-Tech Infant Suit for Earlier Detection of Cerebral Palsy Advanced: May allow for earlier detection of motor dysfunctions in order to begin therapeutic interventions as soon as possible Robust: Collects data from three limb segments on the leg for a multifaceted assessment Long-lasting: Uses one power source with regulated voltage in order to prolong the use of the device	7949
LoCHAid: An Ultra-Low-Cost and Self-Fitting Hearing Aid Low cost: Uses widely available components that cost 98 cents when purchased in bulk quantities User friendly: Easier to fit—and keep track of—than conventional behind- and in-the-ear hearing aids Accessible: Designed for easy manufacture and repair in locations where conventional hearing aids are priced beyond the reach of most citizens	7876
Facilitating Ultrasound Penetration of the Skull for Diagnosis and Treatment Portable: Designed to enable imaging of the brain via small, mobile ultrasound devices, which may offer greater convenience compared with MRI and CT machines Affordable: May be a lower cost modality compared with leading techniques, such as MRI, CT, or positron emission tomography (PET) Robust: Demonstrates energy transmission through the skull on par with that of an aqueous medium in preliminary testing	8340
Near-Real-Time Positioning for Instruments and Tools in Magnetic Resonance Elastography (MRE) and Imaging (MRI) Precise: Extremely precise positioning mechanism enables orientation and control capable of sub-millimeter motions within the MR environment Rapid: Significantly speeds up procedure time over standard MRI and offers wavefield images in near real time High resolution: Uses high-frequency actuation to enable imaging of small, geometrically difficult targets	8412
A Partial-Hand Prosthesis Simulator Specific: Designed to maintain limb length by placing artificial fingers in positions similar to where they would be in an intact hand performing grasping actions (rather than extending the length of the limb as many prostheses do) User friendly: Features rubber-capped fingertips that may provide a more lifelike representation of grasp and enhance usability Nuanced: Designed to limit tactile sensation and feedback from immobilized fingers, which may allow better evaluation of how the device is functioning for the patient in comparison to an actual prosthesis	8534
Portable Multi-Parameter Cancer Diagnostic Tool Powerful: Simultaneously measures multiple tissue parameters to determine electro-thermo-mechanical properties Disposable: Uses single-use biochip components to eliminate cross-contamination Versatile: Uses a variety of other micromotion-capable actuators and extends to other manufacturing techniques and different length scales	7619
Next-Generation Custom-Fit Reusable Mask for Respiratory Protection Aims to eliminate fit-testing: Designed to remove the expensive and time-consuming federal (i.e., OSHA) mandate for annual fit-testing for workplace use Improved fit: Adapts to fit specific facial features, increasing comfort and enhancing efficacy and potentially eliminating face-seal leakage to enhance performance Reusable: Withstands cleaning and decontamination	6635
Vest-Style Device Assists Ventilation and Perfusion (V/Q) to Help Prevent Respiratory Failure Powerful: Designed to optimize oxygenation for patients in acute hypoxic respiratory failure Supportive therapy: Non-invasively complements mechanical ventilator support Low cost: Significantly less expensive than technologies that increase oxygenation (e.g., ventilators, oxygen systems)	8529
Novel Polymer Hybrid Improves Stability of Implantable Devices Strong: Provides structural stability and enhanced cellular adhesion for implant materials Biocompatible: Reduces the risk for complications that could arise with the use of chemical components Customizable: Permits easy incorporation of various nanomaterials to fine-tune devices to meet patient needs	8449

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